Strategic Global Clinical Program Lead – Rare Diseases

EPM Scientific; England; On-site; GBP 120,000 - 150,000; Full time

Job summary

EPM Scientific is seeking an experienced leader to head global and European clinical programs in a rare disease portfolio. The role spans planning through execution and completion, aligning with corporate objectives and maintaining rigorous timelines, budgets, and quality metrics.

You will coordinate cross-functional teams across Clinical Operations, Medical Affairs, Regulatory Affairs, Biometrics, Drug Safety, and external partners to drive delivery and regulatory readiness.

Responsibilities

• Clinical Program Leadership: Lead global and European clinical programs across a rare disease portfolio from planning through execution and study completion.
• Clinical Program Leadership: Drive program delivery, ensuring alignment with broader clinical development and corporate objectives.
• Clinical Program Leadership: Maintain oversight of timelines, budgets, quality metrics, risk management, and overall program performance.
• Clinical Execution & Delivery: Ensure operational excellence across all stages of clinical trial delivery.
• Clinical Execution & Delivery: Provide oversight of study conduct, patient safety, data integrity, and regulatory compliance.
• Clinical Execution & Delivery: Support protocol development and implementation of Quality by Design principles.
• Clinical Execution & Delivery: Review clinical data, study progress, and key performance indicators to drive informed decision-making.
• Cross-Functional Leadership: Lead multidisciplinary project teams to deliver program objectives efficiently and effectively.
• Cross-Functional Leadership: Foster strong collaboration between internal functions and external stakeholders.
• Cross-Functional Leadership: Drive accountability and alignment across all program contributors.
• Site & Vendor Oversight: Oversee site feasibility, site selection, contracting, budgets, recruitment, and operational performance.
• Site & Vendor Oversight: Lead vendor selection, governance, and performance management activities.
• Site & Vendor Oversight: Ensure CROs and service providers deliver against agreed timelines and quality expectations.
• Leadership & Team Development: Provide leadership, coaching, and mentorship across clinical teams.
• Leadership & Team Development: Support resource planning and allocation across programs.
• Leadership & Team Development: Develop team capabilities through training, knowledge sharing, and best practice initiatives.
• Innovation & Continuous Improvement: Identify opportunities to enhance clinical trial execution and program efficiency.
• Innovation & Continuous Improvement: Support implementation of innovative approaches, technologies, and digital solutions.

Job description

EPM Scientific is seeking an experienced leader to head global and European clinical programs in a rare disease portfolio. The role spans planning through execution and completion, aligning with corporate objectives and maintaining rigorous timelines, budgets, and quality metrics.

You will coordinate cross-functional teams across Clinical Operations, Medical Affairs, Regulatory Affairs, Biometrics, Drug Safety, and external partners to drive delivery and regulatory readiness.