Skin Biology Scientist / Senior Research Technician

BiotixAI; Doncaster; On-site; GBP 32,000 - 54,000; Full time

Job summary

BiotixAI is seeking a Skin Biology Scientist / Research Technician to support the development and execution of in vitro and ex vivo skin assay platforms at our Oxford BioEscalator site. This hands-on role targets different seniorities with direct experience in advanced skin models.

You will establish skin organoculture, 3D skin equivalents, culture keratinocytes and fibroblasts, perform IHC and imaging, RNA work, and contribute to SOPs while operating in a small, fast-moving startup.

Qualifications

• Hands-on experience with skin organoculture and 3D skin in vitro models.
• Experience with primary keratinocytes and fibroblasts.
• Experience with IHC, imaging, and molecular readouts.
• Ability to work independently and reliably.
• Detail-oriented approach to laboratory work.
• Comfortable in a small, fast-moving startup.
• Fluent in English (written and oral).

Responsibilities

• Establish, maintain, and run skin organoculture / ex vivo human skin models
• Develop and operate 3D skin equivalent / reconstructed skin in vitro models
• Culture immortalised skin cell lines and primary human keratinocytes and fibroblasts
• Perform immunohistochemistry (IHC) and imaging-based readouts
• Carry out RNA extraction and RT-qPCR
• Culturing microbes and probiotics
• Support experimental design, execution, and troubleshooting
• Implement and follow existing SOPs and protocols
• Manage laboratory consumables, ordering, and suppliers
• Maintain accurate experimental records and documentation
• Contribute to technical and scientific discussions to support R&D milestones

Skills

Hands-on skin organoculture

3D skin models

Primary keratinocytes

Fibroblasts

IHC / imaging readouts

RNA extraction / RT-qPCR

Independently working

Detail-oriented lab work

Startup environment

Fluent English

Education

MSc or PhD in life sciences

Tools

Imaging equipment

Cell culture facilities

Job description

? We’re hiring | Skin Biology Scientist / Research Technician

? Oxford - BioEscalator Headington | Full Time or Part-time 6months contract

Biotix is an early-stage biotech developing biology-first, data-driven platforms to support innovation in skin health, microbiome science, and applied R&D.

We work with international industry partners to translate advanced biological models into robust, decision-ready skin assays that can be reliably used in industrial and translational settings.

As part of a new skin biology program, we are looking for a Skin Biology Scientist / Research Technician to support the development and execution of in vitro and ex vivo skin assay platforms.

This is a hands-on, applied laboratory role. We will consider candidates at different levels of seniority, provided they have direct, practical experience with advanced skin models.

The role can be full-time or part-time, based in Oxford BioEscalator, with flexibility depending on experience and availability.

Working style

We value a pragmatic, proactive, execution-focused approach, with clear alignment and the ability to work with minimal supervision within a small, fast-moving team.

Major Responsibilities

• Establish, maintain, and run skin organoculture / ex vivo human skin models
• Develop and operate 3D skin equivalent / reconstructed skin in vitro models
• Culture immortalised skin cell lines and primary human keratinocytes and fibroblasts
• Perform immunohistochemistry (IHC) and imaging-based readouts
• Carry out RNA extraction and RT-qPCR
• Culturing microbes and probiotics
• Support experimental design, execution, and troubleshooting
• Implement and follow existing SOPs and protocols, avoiding unnecessary reinvention
• Manage laboratory consumables, ordering, and suppliers
• Maintain accurate experimental records and documentation
• Contribute to technical and scientific discussions to support R&D milestones

Basic Qualifications and Essential Skills

• Hands-on experience with skin organoculture and/or 3D skin equivalent in vitro models
• Experience working with primary keratinocytes and fibroblasts
• Experience with IHC, imaging, and molecular readouts
• Ability to work independently and reliably
• Practical, detail-oriented approach to laboratory work
• Comfortable working in a small, fast-moving startup environment
• Fluent in English (written and oral)

Preferred Qualifications

• Experience in industrial, CRO, or translational R&D environments
• Familiarity with skin biology in cosmetic or dermatological contexts
• Willingness to learn additional techniques as required by the project
• MSc or PhD in a relevant life science discipline, or equivalent practical experience

Our websites

www.theskinbiomeco.com

www.biotix.bio