Senior Systems Engineer

TTP; Cambridge; On-site; GBP 60,000 - 80,000; Full time

Job summary

A biotech firm is seeking a Senior Systems Engineer to shape the architecture of an automation system for cell therapies. Responsibilities include defining system requirements, ensuring compliance with standards, and maintaining user perspectives. Candidates should have a strong engineering background, hands-on product delivery experience, and expertise in managing requirements. The role is full-time on-site in Melbourn, UK, offering a range of competitive employee benefits.

Benefits

Annual profit-related bonus

25 days holiday

10% employer pension contribution

Free lunch

Private medical insurance

Enhanced family leave

Life insurance worth 6x salary

Electric car leasing scheme

Cycle to work scheme

Season ticket loan

Qualifications

• Strong academic background in Engineering.
• Experience in developing and delivering products into manufacture.
• Expertise in structured requirements hierarchies.

Responsibilities

• Define and manage system and product-level requirements.
• Drive compliance with regulatory and quality standards.
• Facilitate complex decision-making processes among stakeholders.

Skills

Hands-on product delivery experience

Requirements management expertise

Critical thinking

Collaboration and stakeholder alignment

Ability to visualize data

Education

Engineering degree or vocational qualification

Systems engineering lifecycle experience

Tools

DOORS

Jama

Job description

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Company Description

Cell therapies have been shown to cure devastating and previously untreatable diseases like cancer by re-programming the patient's own immune system. Giving more patients access to these life-saving therapies requires a revolution in manufacturing and process automation.

Cellular Origins, a TTP Company, is enabling scalable, cost-effective and efficient manufacture of cell and gene therapies. Our technology addresses the challenges associated with manufacturing at scale with an elegant robotic manufacturing automation solution that reduces cost and labour, eliminates human error, and increases efficiency.

Job Description

We are seeking a Senior Systems Engineer, this is a unique opportunity to shape the architecture of an end-to-end automation system that will make advanced cell therapies more accessible to patients around the world.

In this role, you will be a key contributor in defining, decomposing, and managing system and product-level requirements, with a strong focus on traceability and interface management across the development lifecycle. You will lead structured requirements processes-from capturing user needs to ensuring verification and validation-while identifying key technical risks, trade-offs, and interdependencies.

Your responsibilities will include driving the adoption of tools and practices that support compliance with regulatory and quality standards, as well as producing robust technical documentation to maintain system-level traceability and alignment.

As a senior member of the team, you will act as a facilitator for complex, cross-functional decision-making processes, aligning diverse stakeholders around shared goals and clear, data-driven choices. You will track critical decisions and manage unresolved issues across phases of development, from concept to final delivery.

You will also maintain a strong customer and user perspective, helping to translate customer needs into engineering requirements and contributing to the development of systems that meet real-world use cases and expectations. Collaboration will be central to your role, as you work closely with stakeholders across engineering, biology, product, and manufacturing to ensure technical cohesion and alignment.

Qualifications

• A strong academic background in Engineering, gained either by degree or vocational route.

• Proven, extensive, hands-on experience developing and delivering products into manufacture.

• Demonstrated expertise in establishing and managing structured requirements hierarchies including the use of tools such as DOORS, Jama, or equivalent.

• Understands and deals well with rapid development cycles.

• Knowledge of product development and manufacturing processes.

• Able to generate clear and accurate visualisations of quantitative data.

• Demonstrated creative and critical thinking capabilities.

• Able to comprehend, communicate and manage complex design trade-off decisions.

• Systems engineering, requirements management, decision analysis operations research education preferred .

• Experience across the systems engineering lifecycle from requirements through to project completion, ideally within a factory automation and/or pharmaceutical setting.
• This role will be a full time on-site position at our campus in Melbourn.

Additional Information

Cellular Origins is part of TTP Group, an employee-owned business. It is based on the TTP Campus, within purpose-built sustainable offices, labs and green surroundings, 10 miles south of Cambridge. TTP Group takes a long-term approach to investment and has been at the forefront of bioprocess automation for over 20 years. Our working culture encourages entrepreneurship, shared ideas and collaboration, while providing you the freedom to do your best work.

Our employee benefits include:

• Annual profit-related bonus
• 25 days holiday
• Employer pension contribution of 10% of salary
• Free lunch and all-day refreshments
• Private medical insurance for employees and dependants
• Enhanced family friendly leave
• Life insurance worth 6x salary
• Electric car leasing scheme
• Cycle to work scheme
• Season ticket loan
• An activities and community fund that supports healthy activities that bring colleagues together; whether it's lunchtime squash or football, Zumba or our own rock band. Colleagues initiate new clubs and outings whenever they feel there's something missing!
• Local sports facilities and theatre discounts and memberships.