Senior Statistician

Roche Holding AG; Welwyn; Hybrid; GBP 60,000 - 90,000; Full time

Job summary

Roche Holding AG in Welwyn is seeking a Senior Statistician to lead statistical input for clinical trial design and analysis. The role supports regulatory submissions and ensures rigorous statistical methodology across development programs.

The ideal candidate has a PhD/ MSc in Statistics and at least 3 years in pharmaceutical statistics, with proficiency in SAS or R and familiarity with CDISC standards. Strong communication and autonomous collaboration across global teams are essential.

Qualifications

• Holds MSc or PhD in Statistics, Biostatistics, or a closely related field.
• Experience in clinical trial statistics within pharma/biotech/CRO.

Responsibilities

• Lead statistical input into clinical trial design and study objectives.
• Develop and review statistical study documents and SAPs.
• Perform or supervise data analyses and interpret results for regulatory submissions.
• Mentor less experienced statisticians and collaborate with cross-functional teams.

Skills

Autonomy

Cross-functional collaboration

Communication skills

Education

MSc or PhD in Statistics/Biostatistics

Tools

SAS

R

CDISC standards

Job description

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

Senior Statistician

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.

This role is within Biostatistics, a core function within Product Development Data Science and Analytics (PDD) that provides strategic leadership and scientific rigor across Development at Roche. Biostatistics identifies opportunities to apply the full breadth of data, digital, and design capabilities to deploy innovative methods across PDD, PD and the broader Roche Pharma organization.

As trusted analytical partners in end-to-end drug development, Biostatistics leverages data to drive scientifically rigorous programmatic decisions across Roche’s Development portfolio; Biostatistics designs robust trials and analysis plans that increase the probability of technical success, accelerating timelines to advance Roche’s clinical pipeline and promote regulatory success — ultimately bringing medicines to our patients faster.

The Opportunity:

The Statistician is a key member of the cross-functional study or molecule team, responsible for applying statistical expertise to the design, conduct, analysis, and interpretation of individual clinical trials. This role ensures the scientific rigor and regulatory compliance of the study by contributing to protocol development, authoring statistical analysis plans, performing or overseeing data analyses, and supporting the interpretation and communication of results. The Statistician plays a critical role in ensuring that each study generates robust, meaningful data to support decision‑making and regulatory submissions.

• You independently lead statistical input into clinical trial design, aligning with scientific objectives
• You own the development and quality review of statistical study documents
• You design and execute complex analyses, proactively resolving challenges
• You represent Biostatistics and PDD at the Study Team level, ensuring statistical and scientific rigor of study deliverables
• You collaborate proactively with cross-functional teams to align deliverables and timelines
• You interpret and communicate results in context, influencing study‑level decisions
• You lead statistical contributions to CSRs and selected regulatory documents
• You provide functional guidance and informal mentoring to less experienced statisticians
• You may lead or influence study‑level projects or contribute significantly to large project teams or initiatives

Who You Are:

• You hold an MSc or PhD in Statistics, Biostatistics, or a closely related quantitative field
• You have a minimum of 3 years of relevant experience in clinical trial statistics within a pharmaceutical, biotech, or CRO setting
• You have demonstrated experience contributing to the design, analysis, and interpretation of clinical studies across different phases
• You have a solid understanding of regulatory expectations and statistical methodologies for clinical development
• You are proficient in SAS and/or R and familiar with CDISC standards
• You are able to work autonomously while collaborating effectively in cross‑functional teams
• You demonstrate capacity for independent thinking and ability to make decisions based upon sound principles
• You bring excellent strategic agility including problem‑solving and critical thinking skills, and agility that extends beyond the technical domain
• You demonstrate respect for cultural differences when interacting with colleagues in the global workplace
• You have excellent verbal and written communication skills, specifically in the areas of presentation and writing, with the ability to explain complex technical concepts in clear language

Preferred:

• Experience working in cross‑functional global study teams.
• Effective communication skills with the ability to translate complex statistical concepts for non-statistical audiences.
• Experience with multiple phases of drug development (early and/or late stage).
• Experience in mentoring or scientific leadership within a matrix organization.
• Strategic mindset with the ability to contribute to portfolio-level decisions

Location

• This position is based in Welwyn

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life‑changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.

The statements herein are intended to describe the general nature and level of work being performed by employees, and are not to be construed as an exhaustive list of responsibilities, duties, and skills required of personnel so classified. Furthermore, they do not establish a contract for employment and are subject to change at the discretion of Roche Products Ltd. At Roche Products we believe diversity drives innovation and we are committed to building a diverse and flexible working environment. All qualified applicants will receive consideration for employment without regard to race, religion or belief, sex, gender reassignment, sexual orientation, marriage and civil partnership, pregnancy and maternity, disability or age. We recognise the importance of flexible working and will review all applicants’ requests with care. At Roche difference is valued and we are proud to be an equal opportunity employer where you are encouraged to bring your whole self to work.