Senior Scientist (protein expression systems) in Bracknell

Energy Jobline ZR; Bracknell; On-site; GBP 80,000 - 100,000; Full time

Job summary

A leading biotechnology organisation in Bracknell is seeking a dynamic Senior Scientist to lead upstream process development for recombinant protein production. This 2-year contract role offers the chance to influence scientific direction within a multidisciplinary team. The ideal candidate will have over 8 years of experience in upstream bioprocessing. Enjoy excellent onsite facilities and training opportunities.

Benefits

On-the-job training

Large campus environment

Excellent onsite facilities, including a site restaurant and gym

Qualifications

• 8+ years of hands-on experience in upstream bioprocessing.
• Strong understanding of upstream decisions impacting downstream processing outcomes.
• Excellent communication skills to present complex concepts clearly.

Responsibilities

• Spearhead upstream process development for recombinant protein production.
• Provide scientific leadership and technical guidance to team members.
• Champion optimisations in upstream processes using a data-led approach.

Skills

Hands-on experience in upstream bioprocessing

Recombinant protein expression

Troubleshooting and innovative problem-solving

Excellent communication skills

Education

Post Doc or equivalent experience in Biotechnology or Microbiology

Tools

Bioreactors

Tangential Flow Filtration (TFF)

Ambr250 micro bioreactor systems

Job description

Senior Scientist (2-year contract)

Our client is seeking a dynamic and passionate Senior Scientist to join a multidisciplinary team.

Role Overview

As a Senior Scientist, you will spearhead our upstream process development for recombinant protein production. This is a fantastic opportunity to influence both scientific direction and team growth over a 24-month contract.

Key Responsibilities

• Lead the charge in upstream process development, focusing on recombinant protein production.
• Provide scientific leadership and technical guidance to team members and project teams.
• Translate expression optimisation from shake flasks to bioreactors as the technical lead.
• Design and refine expression methods to enhance protein quality.
• Investigate how expression conditions affect protein quality attributes across key projects.
• Collaborate across functions to drive overall process improvements.
• Champion optimisations in upstream processes using a data‑led approach.
• Ensure compliance with company HSE policies while working safely.

Essential Qualifications

• Post Doc or equivalent experience in Biotechnology, Microbiology, or related disciplines.
• 8+ years of hands‑on experience in upstream bioprocessing with expertise in:

• Recombinant protein expression (bacterial, insect, yeast, or plant systems).
• Working with bioreactors and transferring shake flask processes into bioreactors.
• Protein purification methods and techniques.

• Strong troubleshooting and innovative problem‑solving abilities.
• Comprehensive understanding of how upstream decisions impact downstream processing outcomes.
• Excellent communication skills to present complex concepts clearly.

Desirable Experience

• Knowledge of construct design and its impact on protein expression.
• Familiarity with AI tools for experimental design.
• Experience with Ambr250 micro bioreactor systems.
• Background in protein characterisation to validate protein quality.
• Experience with scalable bioprocess technologies, such as Tangential Flow Filtration (TFF).
• Industry experience in Biopharma, AgriTech, or related sectors.

Why Join them?

At their organisation, you'll not only be part of an innovative team but also enjoy a range of fantastic perks:

• On‑the‑job training to enhance your skills.
• A large campus environment fostering collaboration.
• Excellent onsite facilities, including a site restaurant, gym, and a variety of fitness classes.