Senior Scientist, Diagnostic Deployment & Digital Pathology

AstraZeneca; Cambridge; On-site; GBP 60,000 - 90,000; Full time

Job summary

AstraZeneca Cambridge invites a Senior Scientist to lead tissue-based assay development and validation. You will ensure analytical rigor, regulatory alignment, and robust data capture across clinical studies, while integrating LIMS and digital pathology for streamlined workflows.

We seek a professional with expert IHC, QA, and cross-functional collaboration skills to support diagnostics across our oncology portfolio in a highly regulated lab environment.

Qualifications

• Degree in Biomedical Science, Pathology, Life Sciences, or equivalent.
• Strong practical experience in histology and immunohistochemistry (IHC) in a regulated lab.
• Experience supporting routine lab operations and workflow coordination.
• Experience with prospective diagnostic testing or clinical-study labs.
• Experience with LIMS/LIS and digital pathology.
• Knowledge of CAP/CLIA, ISO standards, IVDR, HTA, HBS.
• Experience with SOPs, deviations, CAPAs, and audit readiness.
• Strong data integrity, documentation and cross-functional collaboration.

Responsibilities

• Lead development, validation, and delivery of tissue-based assays ensuring consistency and turnaround.
• Design analytical validation plans aligned with regulatory expectations.
• Apply whole-slide imaging and image analysis to strengthen scoring and interpretation.
• Embed CAP/CLIA, ISO, IVDR and HTA requirements in daily lab practice and audits.
• Support prospective diagnostic testing for clinical studies with GCP ICH adherence.
• Improve end-to-end workflows by integrating LIMS and related systems.
• Lead cross-functional projects with clinical, regulatory, and quality teams.
• Drive scientific innovation by assessing new tissue-based technologies.

Skills

Histology & IHC

Regulatory compliance

Cross-functional collaboration

Data integrity & documentation

Clinical lab operations

Digital pathology

Education

Biomedical Science degree or equivalent

Tools

LIMS/LIS

Whole-slide imaging

Image analysis software

Job description

AstraZeneca Cambridge invites a Senior Scientist to lead tissue-based assay development and validation. You will ensure analytical rigor, regulatory alignment, and robust data capture across clinical studies, while integrating LIMS and digital pathology for streamlined workflows.

We seek a professional with expert IHC, QA, and cross-functional collaboration skills to support diagnostics across our oncology portfolio in a highly regulated lab environment.