Senior Scientist

Next Phase Recruitment Limited; Oxford; On-site; GBP 50,000 - 70,000; Full time

Job summary

A biotechnology recruitment firm in Oxford is seeking an experienced Senior Scientist – Formulation to develop nanoparticle-based formulations for cutting-edge mRNA therapeutics. The ideal candidate will have a Ph.D. and strong expertise in biomaterials, with experience in developing and characterizing formulations for pharmaceuticals. This role emphasizes collaboration and innovation in a fast-paced environment.

Qualifications

• Demonstrated expertise in nanoparticle assembly and characterization.
• Strong knowledge of biophysical and physicochemical characterization techniques.
• 1-2 years of relevant industry experience is advantageous.

Responsibilities

• Lead the development of nanoparticle formulations for mRNA therapeutics.
• Design experimental study plans for optimizing formulations.
• Collaborate with cross-functional teams including RNA synthesis and biology.

Skills

Nanoparticle assembly

Biomaterials

Formulation development

Analytical skills

Communication

Education

Ph.D. in Chemistry, Pharmaceutical Sciences, Biology, or Physics

Tools

SAXS

DSC

NMR

LC-MS

HPLC

DLS

TEM

Job description

Company Overview

I am working with an innovative biotechnology company developing a cutting‑edge LNP platform to advance mRNA vaccines and therapeutics across a wide range of diseases. Their mission is to make mRNA‑based treatments accessible to everyone, everywhere, addressing critical global health challenges such as antibiotic resistance, cancer, and viral illnesses. They aim to be a leader in the life sciences sector by applying advanced science and technology to improve human health.

Role Overview

We are seeking a highly motivated Senior Scientist – Formulation to join our R&D team. The successful candidate will play a key role in the design, development, and optimization of nanoparticle‑based formulations for mRNA pharmaceuticals. This position requires strong expertise in nanoparticles, biomaterials, and polymers, with hands‑on experience in formulation development and characterization.

Key Responsibilities

• Lead the development of nanoparticle formulations for mRNA therapeutics.
• Design experimental study plans to optimize formulations for specific RNA constructs and therapeutic applications.
• Develop nanoparticle manufacturing processes for in‑house use and transfer to external GMP facilities.
• Collaborate closely with cross‑functional teams, including RNA synthesis, biology, and analytics.
• Prepare technical documents, reports, and presentations for management and external partners.
• Maintain high standards of quality, reproducibility, and rigor in experimental research and development activities.

Education & Experience

• Ph.D. in Chemistry, Pharmaceutical Sciences, Biology, Physics, or a related field with a focus on bio‑ or nano‑materials.
• Demonstrated expertise and practical experience in nanoparticle assembly and characterization, preferably lipid‑ or polymer‑based nanoparticles.
• Strong knowledge of biophysical and physicochemical characterization techniques (e.g., SAXS, DSC, NMR, LC‑MS, HPLC, DLS, TEM).
• 1‑2 years of relevant industry experience is advantageous.

Required Skills & Abilities

• Highly organized, self‑motivated, and structured, with the ability to prioritize development goals effectively.
• Excellent time‑management skills and ability to meet deadlines in a fast‑paced environment.
• Strong analytical and problem‑solving skills, with the ability to work independently.
• Resilient and adaptable in high‑pressure or rapidly changing environments.
• Excellent communication skills and ability to collaborate in an interdisciplinary, multicultural team.