Senior Research Nurse | Guy's and St Thomas' NHS Foundation Trust

Guys and St Thomas NHS Foundation Trust; City Of London; On-site; GBP 40,000 - 55,000; Full time

Job summary

A leading healthcare trust in London is looking for an exceptional senior research nurse to provide clinical leadership for a rapidly expanding research portfolio. The successful candidate will oversee patient recruitment for clinical trials, ensuring high-quality research delivery and coordination of patient pathways. Knowledge in oncology and experience in managing clinical trials are essential for this role.

Qualifications

• Experience in managing clinical trials and patient recruitment.
• Proven ability to work autonomously with large caseloads.
• Strong understanding of EU clinical trial directives.

Responsibilities

• Manage large caseload of patients, ensuring duty of care.
• Coordinate research patient pathway from screening through trial closure.
• Act as a resource and support for patients and families.

Skills

Clinical leadership

Patient management

Oncology knowledge

Phlebotomy

Education

Nursing qualification

Job description

Overview

We are looking for an exceptional senior research nurse to join the MPN (Myeloproliferative Neoplasm) Research Team within Oncology and Haematology Clinical Trials (OHCT) team. This post is to provide clinical leadership for our rapidly expanding research portfolio, and support the team to deliver high-quality research. The successful candidate will work alongside the Team Lead. You will be responsible for identifying patients suitable for entry into clinical trials by attending clinics (screening notes/consultant referral) and Multidisciplinary Team (MDT) meetings. Participate in the informed consent process acting as a resource and support to patients and their families and coordinate the research patient pathway from screening through to trial closure, creation of prompts at the setup stage of the trial.

OHCT sits within the Haematology Directorate. The team runs and manages over 200 trials at any one time and covers all solid tumours, haematological malignancies and non-malignant diseases. We have a dedicated team running the early phase studies and are part of ECMC based in the clinical research facility.

Responsibilities

• Work autonomously to manage a large caseload of patients, acting as a professional in ensuring a duty of care to the patient and their families.
• Work within EU clinical trial directives in accordance with ICH GCP, ensuring that the clinical trial protocol is adhered to at all times.
• Identify patients suitable for entry into clinical trials by attending clinics (screening notes/consultant referral) and MDT meetings.
• Participate in the informed consent process acting as a resource and support to patients and their families.
• Coordinate the research patient pathway from screening through to trial closure, including creation of prompts at the setup stage of the trial.
• Ensure adequate precautions are taken to minimise the risk of cross-infection in relation to the safe disposal of body fluids including blood products.
• Support the administration of trial drugs, be aware of and report any side effects as outlined in the protocol, in association with local nursing teams.
• Maintain adequate patients’ records and ensure all relevant information is documented in the patient’s medical and nursing notes.
• Responsible for accurate completion of Clinical Report Forms (CRFs).
• Responsible for the collection, coordination and computerisation of data generated from the clinical trials.
• Keep up to date with current practices for cannulation, phlebotomy, care of patients with Central Venous Access lines and handling and administration of systemic anti-cancer therapy (SACT) and Investigational Products (IP).
• Identify strategies for recruiting patients to clinical trials and support less experienced team members to implement those strategies.
• Act as a role model for excellence in oncology/haematology-based research.
• Act as the keyworker for trial patients throughout their clinical trials treatments, liaising with the medical and Clinical Nurse Specialist (CNS) team.
• Signpost/referral of trial patients to supportive care services.
• Review trial protocols and identify risk and resource implications for the site.
• Attend pre-study visits and review protocol at feasibility stage to map patient pathways, highlighting issues and potential resolutions to ensure patient safety.
• Liaise with the medical team/sponsor organisation and coordinate on-study treatment and follow up of patients.
• Liaise with Clinical Trial Set Up staff and Team Lead to assist in the on-site set-up of trials.
• Assist in completing submissions to Research & Development departments of relevant sites where applicable.
• Process amendments and disseminate information to relevant departments.
• Supervise the research team in the collation of data generated from clinical trials.
• Provide information to allow for invoicing where appropriate.
• Build strong professional relationships with other departments to promote a good working environment.
• Educate appropriate medical and nursing personnel and departments about the portfolio of clinical trials.
• Participate in the presentation of research findings within the Trust and other networks.
• Manage clinical incidents effectively and report to the Cancer Clinical Governance Team any clinical incidences with follow-up to conclusion.
• Maintain a dialogue of progress with the Clinical Research Matron and the Clinical Trials Manager.
• Attend monthly portfolio performance review meetings and identify and act on issues.
• Provide cover when necessary for annual leave, study leave, sick leave.
• Assist in recruitment and selection of the research staff throughout the Trust.
• Contribute to yearly business planning to ensure the research team is properly structured and resourced at all times.
• Take the lead in service development for the research team, directorate and the Trust.
• Develop and implement the key worker concept within the Research Team.
• Develop and implement strategies to maintain and increase patient recruitment into cancer clinical trials within GSTFT.
• Maintain the high profile of GSTFT in line with the Cancer strategy.
• Innovate and contribute to the development of Network-wide clinical and research policies and procedures.
• Work with the team leader to ensure the Trust meets accrual targets for NCRN and commercial trials and address any shortfalls.
• Contribute to implementing strategies and systems for quality assurance.
• Attend training programmes and other relevant education days as agreed in your development plan.
• Attend investigator meetings and conferences when required.
• Take personal responsibility for professional growth and keep up to date with professional development and research.
• Prepare posters/research papers for meetings, conferences and publications.
• Represent the research team at local and national forums and participate in service development.
• Mentor and support other team members and participate in clinical supervision as both supervisor and supervisee in accordance with NMC guidelines.
• Undertake performance reviews at regular intervals and manage adherence to trust policies throughout the team.
• Act up for Team Lead and Research Matron as required.

This advert closes on Monday 13 Oct 2025