Senior/Principal Biostatistician – Early Phase, EMEA

Syneoshealth; United Kingdom; Remote; GBP 90,000 - 130,000; Full time

Job summary

Syneos Health is seeking a Sr/Principal Statistician (Sponsor-dedicated) for Early Phase work across multiple locations in the EMEA region. The role involves leading biostatistics activities through the full project lifecycle, developing SAPs, and coordinating with biostatistics and programming teams to deliver high‑quality analyses and reports.

You will contribute to protocol development, statistical sections, and safety monitoring activities, while ensuring compliance with ICH guidelines and

Responsibilities

• Provides support across all assigned statistical tasks during the lifecycle of the project, from protocol to CSR.
• Prepares Statistical Analysis Plans (SAPs), including development of mock‑up displays for tables, listings, and figures.
• May be responsible for the statistical aspects of the protocol, generation of randomization schedule, publications and input to the clinical study report.
• Coordinates activities of other biostatistics and statistical programming personnel to ensure timely completion of high‑quality work.
• Creates or reviews programming specifications for analysis datasets, tables, listings, and figures.
• Reviews SAS annotated CRFs, database design, and other study documentation to ensure protocol criteria are met and data captured.
• Conducts verification and quality control of project deliverables, ensuring output aligns with SAP and specifications.
• Implements company objectives and creates alternative solutions to address business challenges.
• Serves as biostatistics representative on project teams and interfaces with other departmental representatives.
• Manages scheduling and time constraints across multiple projects and communicates potential delays to management.
• Monitors progress on study activities against milestones and escalates out‑of‑scope tasks as needed.
• Provides statistical programming support as needed.
• May participate in Data Safety Monitoring Board activities as an independent biostatistician.
• May lead projects involving integrated analyses and regulatory interactions as needed.
• Follows SOPs and regulatory guidelines and maintains inspection readiness.
• Displays willingness to collaborate and supports business development through proposals and sponsor meetings.
• Coaches and mentors Biostatistics staff.
• Performs other duties; minimal travel may be required.

Job description

Syneos Health is seeking a Sr/Principal Statistician (Sponsor-dedicated) for Early Phase work across multiple locations in the EMEA region. The role involves leading biostatistics activities through the full project lifecycle, developing SAPs, and coordinating with biostatistics and programming teams to deliver high‑quality analyses and reports.

You will contribute to protocol development, statistical sections, and safety monitoring activities, while ensuring compliance with ICH guidelines and