Senior Postdoctoral Researcher

University of Oxford; Oxford; On-site; GBP 38,000 - 50,000; Full time

Job summary

A prestigious academic institution in Oxford is seeking an enthusiastic senior postdoctoral researcher to lead a project on T cell genomics. Applicants should possess a PhD and relevant postdoctoral experience, with expertise in functional genomic screening. This role offers a fixed-term contract and a range of generous benefits, including 38 days of annual leave and a contributory pension scheme.

Benefits

Excellent contributory pension scheme

38 days annual leave

Comprehensive childcare services

Family leave schemes

Cycle loan scheme

Discounted bus travel

Membership to social and sports clubs

Qualifications

• PhD in a relevant field and postdoctoral experience required.
• Expertise in functional genomic screening in primary T cells.
• Ability to integrate computational and experimental approaches.

Responsibilities

• Lead a project on signalling via inhibitory receptors in T cells.
• Shape the scientific direction of the group.
• Support future grant development.

Skills

Functional genomic screening

T cell signalling pathways

High-throughput assays

Supervising junior researchers

Grant writing

Education

PhD

Postdoctoral research experience

Job description

We are looking to appoint an enthusiastic and experienced senior postdoctoral researcher to join Dr Sharma's Mechanistic T Cell Genomics group. The candidate will the lead on a project focusing on understanding signalling via inhibitory receptors in T cells using functional genomic screening approaches in primary T cells. The post is funded via the Wellcome Trust and is available as a fixed-term contract for 3 years, with a possibility to extend. If you are interested in this position and have the skills and experience, we are looking for, please apply below. You will be required to upload a CV and supporting statement as part of your online application. Informal inquiries can be sent to Dr Sumana Sharma ([e-mail]). Only applications submitted online and received before midday on Thursday 20th November 2025 will be considered. Interviews will be held as soon as possible thereafter.

You should hold a PhD and postdoctoral research experience for this post. The ideal candidate will have expertise in functional genomic screening in primary T cells and the ability to establish high-throughput assays in T cells. You should have a strong interest in T cell signalling pathways and demonstrate experience in integrating computational and experimental approaches to address key biological questions. Experience in supervising junior researchers and contributing to grant writing would be advantageous. In this role, you will lead a project investigating the similarities and differences among inhibitory receptors in T cells, providing both strategic and hands‑off leadership. You will also play a key role in shaping the future scientific direction of the group and supporting future grant development.

The Radcliffe Department of Medicine (RDM) within the Medical Sciences Division is one of the largest departments in the University of Oxford. RDM is a multi-disciplinary department which aims to tackle some of the world's biggest health challenges by integrating innovative basic biology with cutting edge clinical research.

Benefits of working

As an employer, we genuinely care about our employees' wellbeing and this is reflected in the range of benefits that we offer including:

• An excellent contributory pension scheme
• 38 days annual leave
• A comprehensive range of childcare services
• Family leave schemes
• Cycle loan scheme
• Discounted bus travel and Season Ticket travel loans
• Membership to a variety of social and sports clubs