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Earlham Institute invites applications for a (Senior) Postdoctoral Research Scientist to join the Laboratory of Dr Wojtowicz in Norwich, UK. The project focuses on platelet biology and hematopoietic system interactions, using flow cytometry, genomics, and microfluidics.
The role involves developing microfluidic single-cell methods and collaborating with the Macaulay group, with training and access to FACS facilities. This is a full-time maternity cover lasting ~9 months.
We believe that our people are our greatest asset, and we want you to have the freedom to achieve your very best work here.
Salary range: £39,000 - £58,000
Applications are invited for a (Senior) Postdoctoral Research Scientist to join the Laboratory of Dr Wojtowicz in the Research Faculty of the Earlham Institute, based in Norwich, UK.
The Wojtowicz Group studies the functional and molecular links between diet, and the host immune response and the hematopoietic system. We have a particular focus on platelets and megakaryocytes biogenesis and function.
We apply flow cytometry, lineage tracing, and genomics to study these subjects. We are also actively developing new isolation methods for high throughput and size unbiased cell capture of megakaryocytes and platelets for functional and molecular analysis.
Western diets rich in fat and sugar are associated with obesity, metabolic syndrome diseases, and increased incidence of viral and bacterial infections. Contrary to this is a recent trend for people to reduce their meat intake as part of a healthier lifestyle. This reduction is associated with extended health span and these types of diets are prevalent in Blue zones; areas with increased frequency of centenarians.
Transitioning from meat- to plant-based diets results in an overall reduction in protein intake. However, the impact of low-protein intake in human health remains largely undefined.
In this project, the successful candidate will utilise cell lines, primary animal samples, microfluidics platforms and state of the art flow cytometry, to address fundamental questions in platelet biology, heterogeneity and response to activation.
This position will also involve the technical development of microfluidic single cell encapsulation methods and consecutive analysis by flow cytometry.
The candidate will work closely with the Macaulay group on implementation of the microfluidics and will obtain training from the FACS facility manager to use available FACS analyser. They will have access to the analysis software and can obtain support from other group members for the data analysis.
We believe that our people are our greatest asset, and we want you to have the freedom to achieve your very best work here.
Norwich is a city of culture, with its rich history of art and writing, as well as a city of science - hosting some of the leading centres for life science research in the world.
The behaviours and communication skills we expect from candidates.