Senior Manager, Data Sciences

Bristol-Myers Squibb Co; Denham; Hybrid; GBP 90,000 - 130,000; Full time

Job summary

Bristol Myers Squibb in the United Kingdom is seeking a Senior Manager, Data Science to join the DSAA team, shaping decisions across multimodal clinical and omics data. This hands-on role blends computational science, statistics, and drug development to drive the global development pipeline.

You will lead exploratory and confirmatory analyses, apply ML/NLP techniques, and collaborate with cross-functional teams to deliver insight at scale.

Qualifications

• PhD in a relevant quantitative field with 1+ years of academic/industry experience; or a Master's with 3+ years in industry
• Strong experience in data science and statistical analysis using clinical trial or EHR data in pharma R&D
• Experience developing and validating statistical and ML models on high-dimensional data for time-to-event, longitudinal, and multivariate outcomes
• Experience with Python, R, SQL, and cloud platforms (AWS, Azure, Databricks)
• Familiarity with clinical trial design and biomarker applications in regulatory decisions
• Ability to apply AI/ML, NLP, and explainable AI to diverse data modalities

Responsibilities

• Develop novel computational methods for patient segmentation, biomarker discovery, and hypothesis generation from multimodal data
• Execute analyses on datasets from clinical trials and real-world cohorts across genomics, proteomics, imaging, and high-dimensional biomarkers
• Integrate and visualise diverse datasets across drug development stages
• Formulate, implement, test, and validate predictive models and scalable analysis pipelines
• Apply ML, NLP, causal ML, and explainable AI across data modalities and contexts
• Contribute to statistical strategy and design of drug development programs
• Collaborate with clinicians, statisticians, data engineers, and IT professionals

Skills

Data science

Statistical analysis

Machine learning

Python

R

SQL

NLP

ML modelling

Education

PhD in quantitative field

Master's in quantitative field

Tools

Python

R

SQL

AWS

Azure

Databricks

Job description

At Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it.

Drive Insight at the Cutting Edge of Drug Development

Are you a hands-on data scientist with a passion for turning complex, multi-modal data into actionable insights that shape clinical decisions? Bristol Myers Squibb is seeking a Senior Manager, Data Science to join our Drug Development Data Science & Advanced Analytics (DSAA) team.

This is a new role for a state-of-the-art individual contributor who thrives at the interface of computational science, statistical rigour, and drug development. You will execute and drive exploratory and confirmatory analyses across a rich variety of data types — from clinical trial data to genomics, proteomics, imaging, and beyond — contributing directly to decisions that advance our global development pipeline.

What You'll Do

Data Science & Analytics

• Develop and apply novel computational methods for patient segmentation, biomarker discovery, and hypothesis generation from multimodal clinical and omics datasets, in partnership with Translational, Clinical, and Statistical Scientists
• Execute data science analyses on datasets from BMS clinical trials and real-world data cohorts, spanning genomics, proteomics, imaging, flow cytometry, and other high-dimensional biomarker data types
• Develop innovative approaches to integrating, mining, and visualising diverse, high-dimensional, and disparate datasets generated across early-to-late phase drug development
• Formulate, implement, test, and validate predictive models and build efficient, automated processes for delivering modelling results at scale
• Apply modern machine learning capabilities — including AI/ML, deep learning, NLP, causal ML, and explainable AI — across multiple data modalities and clinical development contexts
• Apply statistically rigorous approaches to clinical trial data, including survival analysis, longitudinal/mixed-effects modelling, and appropriate handling of missing data and censoring
• Contribute to the scientific and statistical strategy of drug development programs, including the development of predictive biomarkers, novel trial designs, and precision medicine approaches

Data Engineering & Reproducibility

• Build and maintain well-structured, reproducible, version-controlled analytical pipelines and codebases using Python, R, SQL, and cloud platforms
• Develop and apply data quality frameworks to assess and ensure fitness-for-purpose of diverse data sources for specific analytical questions
• Implement strong model evaluation practices including cross-validation strategies, calibration assessment, and transparent reporting of model performance and limitations
• Build scalable, automated processes for delivering analytical results across multiple programs and data types

Collaboration & Technical Contribution

• Partner with lead and protocol statisticians in contributing to statistical analysis plans (SAPs) for exploratory data science analyses supporting drug development programs
• Collaborate with cross-functional teams including clinicians, translational medicine scientists, biostatisticians, data engineers, and IT/engineering professionals
• Contribute to team excellence through code reviews, technical mentorship, and raising the overall engineering and methodological standards of the team
• Communicate analytical strategies and results clearly and effectively to both technical and non-technical stakeholders, with strong data presentation and visualisation skills
• Manage and coordinate deliverables across concurrent, fast-paced projects within tight timelines

What We're Looking For

Required Qualifications:

• PhD in a relevant quantitative field (e.g., Computational Biology, Biostatistics, Statistics, Biomedical Engineering, or Computer Science) with 1+ years of academic/industry experience; or a Master's Degree in a relevant quantitative field with 3+ years of industry experience
• Strong experience in data science and statistical analysis using clinical trial or electronic health records data, particularly in a pharma R&D context
• Experience developing and validating statistical and machine learning models on high-dimensional data for time-to-event, longitudinal, and multivariate outcomes
• Experience in the application of AI/ML and proficiency in Python, R, SQL, and cloud platforms (e.g., AWS, Azure, Databricks)
• Familiarity with clinical trial design, drug development processes, and the role of biomarkers in regulatory and clinical decision-making
• A perspective on leveraging innovative approaches to expedite drug development and address the complexities of emerging data types
• Strong problem-solving, collaboration, and communication skills, with the ability to handle several concurrent, fast-paced projects independently and as part of a team

Preferred Qualifications:

• Experience with genomics, proteomics, imaging, flow cytometry, or immunobiology datasets from clinical trials
• Experience with NLP, causal ML, explainable AI, and survival analysis/time-to-event modelling
• Knowledge of molecular biology and understanding of disease pathways
• Experience with real-world data (RWD/RWE) sources and associated analytical methods
• Familiarity with digital health data and wearable/sensor-derived data types
• Experience with cloud-based scalable compute and deployment patterns for large-scale data processing and model training

#LI-Hybrid

We hire for skills and capabilities, not just credentials – if this role excites you, but doesn’t perfectly match your resume, we encourage you to apply anyway.

How We Work

Where you work matters – because collaboration, innovation and patient impact happen in many settings. Our roles are structured across four work models: site-essential, site-by-design, field-based and remote-by-design. The model assigned to this role is based on its core responsibilities. Learn more at https://careers.bms.com/ways-of-working.

Supporting People with Disabilities

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [e-mail]. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Bristol Myers Squibb is Disability Confident – Employer

A UK Government scheme

Candidate Rights

BMS will consider qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

For roles based in Los Angeles County only: If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

Data Protection

We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

If this posting is missing required information required by local law or incorrect, contact BMS at [e-mail] with the Job Title and Requisition number. Do not send application-related inquiries to this email. To check your application status, please login to your Candidate Home Account.

R1600844 : Senior Manager, Data Sciences