Senior Manager, Clinical Scientist, Ophthalmology

Regeneron Pharmaceuticals, Inc; Cambourne; Hybrid; GBP 113,000 - 173,000; Full time

Job summary

Regeneron Pharmaceuticals, Inc. is seeking a Senior Manager to join our Clinical Sciences team, supporting Ophthalmology clinical development programs.

You will help lead the design, execution, and interpretation of clinical studies, partnering with Medical Directors and cross-functional study teams to advance candidates through early and/or late phase development. This role offers hybrid on-site work with flexibility, and the opportunity to contribute to a fast-growing, science-driven

Qualifications

• MS/PhD/PharmD in a related scientific field is required.
• 8+ years of pharmaceutical clinical drug development experience.
• Ophthalmology clinical trials experience is preferred.
• Strong medical writing and regulatory knowledge.
• Proven cross-functional collaboration in a matrix organization.

Responsibilities

• Lead the scientific strategy behind clinical studies from design through execution and reporting.
• Partner with Medical Directors and cross-functional teams to shape protocols, amendments, and study conduct.
• Build deep expertise in disease biology, mechanism of action, and competitive landscape.
• Author and review key trial documents, including expanded synopses, monitoring plans, and study reports.
• Safeguard patient safety through ongoing clinical and medical data review.
• Identify risks to study integrity early and drive practical mitigation strategies.
• Represent Clinical Sciences on program teams, steering committees, and safety monitoring boards.
• Champion consistent, high-quality data review practices across assigned studies.

Skills

Medical writing

Clinical research methodology

GCP/ICH knowledge

Cross-functional collaboration

Ophthalmology trial experience

Education

MS/PhD/PharmD in a related field

Job description

Build our future together:

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Senior Manager to join our Clinical Sciences team, supporting our Ophthalmology clinical development programs. In this role, you will help lead the design, execution, and interpretation of clinical studies, partnering closely with Medical Directors and cross-functional study teams to advance candidates through early and/or late phase development. This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

When & where:

• Location: Tarrytown, NY, Cambridge, MA, or Warren, NJ
• Work Model: Primarily on-site with hybrid flexibility

Discover your role:

• Lead the scientific strategy behind clinical studies from design through execution and reporting
• Partner with Medical Directors and cross-functional teams to shape protocols, amendments, and study conduct
• Build deep expertise in disease biology, compound mechanism of action, and the competitive treatment landscape
• Author and review key trial documents, including expanded synopses, monitoring plans, and study reports
• Safeguard patient safety through ongoing clinical and medical data review
• Identify risks to study integrity early and drive practical mitigation strategies
• Represent Clinical Sciences on program teams, steering committees, and safety monitoring boards
• Champion consistent, high-quality data review practices across assigned studies

This role requires:

• MS, PhD, or PharmD in a related scientific field, plus 8+ years of pharmaceutical clinical drug development experience (other levels considered based on experience)
• Experience in Ophthalmology clinical trials preferred
• Proven knowledge of GCP, ICH guidelines, clinical trial design, and regulatory requirements
• Strong medical writing skills and clinical research methodology expertise
• Demonstrated success working cross-functionally in a matrix organization