Senior Engineer

Oxford BioMedica Limited; Oxford; On-site; GBP 45,000 - 65,000; Full time

Job summary

A leading gene therapy company in the United Kingdom is seeking a Senior Engineer to support cGMP manufacturing processes. The role focuses on managing control systems and operational technologies, ensuring reliability and compliance. You will lead internal projects, troubleshoot equipment issues, and collaborate with various departments. Ideal candidates will possess a degree in engineering, significant experience in a regulated environment, and a proactive problem-solving mindset. The company offers a supportive and innovative culture with emphasis on career development.

Benefits

Competitive total reward packages

Wellbeing programmes

Career development opportunities

Inclusive culture

State-of-the-art labs

Qualifications

• Minimum of 5 years of experience in a cGMP engineering environment.
• Expertise in reliability of process equipment and data systems.
• Strong ability to prioritize and solve complex problems independently.

Responsibilities

• Manage control systems and operational technologies for cGMP manufacturing.
• Lead cross-functional internal projects and ensure schedules are met.
• Troubleshoot equipment and address operational challenges efficiently.

Skills

Control systems

Bioreactor/Filling line background

GMP/Pharma regulations

Manufacturing control systems automation

GAMP software development lifecycle

Network architecture (TCP/IP)

Education

Bachelor's degree in Electrical/Computer/Chemical Engineering

Job description

We're currently recruiting for a Senior Engineer for the Engineering team. In this role, you will utilize Good Engineering Practices (GEP) to establish and maintain the industrial process automation, building automation and operational technology systems required to support cGMP manufacturing and process development. As a system owner, you will be responsible for day‑to‑day operations support and troubleshooting, project execution, commissioning and qualification support, and optimizing process and utilities equipment within a regulated cGMP facility, playing a key part in advancing our mission and making a real difference.

Responsibilities

• Assuming ownership responsibility of control systems and other operational technologies by applying the engineering lifecycle to enable cGMP manufacturing.
• Organizing and leading all aspects of cross‑functional internal projects including scope, schedules, and execution.
• Applying technical expertise in ensuring the reliability of complex process equipment, data, and building and utilities systems.
• Developing solutions and best practices for a variety of problems with moderate scope and complexity, and working collaboratively with Quality, Manufacturing, Facilities, Process Development, external supply partners, and vendors.
• Responding to support calls and troubleshooting equipment and applying evaluation, judgement, and interpretation to resolve issues and select the best course of action.
• Being a Control Systems Engineering representative for capital projects involving building automation, process and utilities equipment for cGMP facilities.

Qualifications

• Technical/ complex equipment systems – Control systems. Bioreactor/ Filling line background. Background in GMP/ Pharma/ regulated environments
  Bachelor's degree in Electrical Engineering / Computer Science / Chemical Engineering or equivalent, with a minimum of 5 years of experience in a cGMP engineering environment, or advanced degree in lieu of experience.
• Significant knowledge and understanding of GMP engineering principles and practices in the gene therapy industry.
• Manufacturing control systems automation background focused specifically on the design, installation, programming, validation, and in‑life cycle maintenance of automated equipment, specifically in a GMP environment.
• Knowledge of GAMP software development lifecycle, ANSI/ISA‑S88 and S95 industry standards, and 21 CFR Part 11.
• Demonstrated experience with network architecture including TCP/IP, routing, switching, network IDS/IPS, Active Directory, domain integration, and firewalls.
• Able to accommodate changing priorities and deadlines and work independently solving complex process and equipment problems.

At OXB, our people are at the heart of everything we do. We're on a mission to enable life‑changing therapies to reach patients around the world—and we're looking for passionate individuals who embody our core values every day: Responsible, Responsive, Resilient, and Respectful. OXB is a quality and innovation‑led viral vector CDMO with a mission to enable its clients to deliver life‑changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, we have more than 25 years of experience in viral vectors; the driving force behind the majority of gene therapies.

OXB collaborates with some of the world's most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno‑associated virus (AAV) and adenoviral vectors. OXB's world‑class capabilities span from early‑stage development to commercialisation. These capabilities are supported by robust quality‑assurance systems, analytical methods, and depth of regulatory expertise.

Why Join Us?

• Competitive total reward packages
• Wellbeing programmes that support your mental and physical health
• Career development opportunities to help you grow and thrive
• Supportive, inclusive, and collaborative culture
• State‑of‑the‑art labs and manufacturing facilities
• A company that lives its values: Responsible, Responsive, Resilient, Respect

We want you to feel inspired every day. At OXB, we're future‑focused and growing fast. We succeed together‑through passion, commitment, and teamwork. Ready to Make a Difference? Collaborate. Contribute. Change lives.