Senior Director Pharmacology

Discover International; Greater London; On-site; USD 107,066 - 200,749; Full time

Job summary

An exciting opportunity awaits at a leading biotech firm in London, seeking a Senior Director for Pharmacology. This pivotal role involves overseeing preclinical development for biologic and small molecule drug candidates, leading discovery teams, and collaborating with scientists to optimize screening strategies. The successful candidate will possess a Ph.D. and over 10 years of drug development experience, with a strong background in preclinical processes. Join a dynamic team that values innovation and scientific excellence, and play a crucial role in advancing groundbreaking therapies from discovery to clinical development.

Qualifications

• 10+ years of drug development experience with extensive preclinical knowledge.
• Proven leadership in managing teams and influencing C-Suite leaders.

Responsibilities

• Lead discovery teams and develop preclinical strategies for drug candidates.
• Oversee preparation of preclinical sections for regulatory documents.

Skills

Drug Development

Preclinical Development

Leadership

Assay Development

Collaboration with CROs

Project Management

Education

Ph.D. in Pharmacology

Ph.D. in Immunology

Ph.D. in Oncology

Ph.D. in Cell Biology

Tools

3D Cellular Models

Functional Genomics Platforms

Job description

Direct message the job poster from Discover International

Finding the 'Needle in the Chaystack' talent

This is an exciting new position for a Biotech company based out of London, looking to strengthen the senior leadership team and scientific expertise by bringing onboard a Senior Director for Pharmacology to oversee all aspects of preclinical development for biologic and small molecule drug candidates into clinical development.

Responsibilities:

• Lead discovery teams by developing preclinical development strategies for drug candidates.
• Team up with scientists and external collaborators to develop preclinical screening strategies for discovery programs, which will include developing and optimizing new assays.
• Lead cross-functional discovery teams.
• Oversee and contribute to the preparation of preclinical sections of regulatory documents.
• Integrate and optimize automation strategies.
• Partner with the team to integrate analysis pipelines for cellular- and patient-derived data sets.
• Establish and manage timelines, budgets, and resources for preclinical programs.

Requirements:

• Ph.D. in Pharmacology, Immunology, Oncology, Cell Biology or related field
• 10+ years of drug development experience
• Extensive experience in preclinical development
• Experience in leading discovery project teams to advance programs from early discovery to candidate selection and IND submission.
• Extensive knowledge of preclinical development processes, including pharmacology, toxicology, PK/PD, and translational science.
• Hands-on experience working with 3D cellular or tissue models to support discovery efforts
• Expertise in developing assays to support biologic and small molecule screening, including functional genomics-based target validation platforms
• Proven experience managing CROs and external collaborations
• Strong leadership and team-building capabilities, including experience managing other managers and influencing C-Suite leaders.

Seniority level

Director

Employment type

Full-time

Job function

Science and Project Management

Industries

Biotechnology Research and Pharmaceutical Manufacturing