Senior Director, ADC Platform & Conjugation Leadership

Vector Laboratories, Inc.; Wilton; On-site; GBP 150,000 - 230,000; Full time

Job summary

Vector Laboratories is seeking a Senior Director/AVP, Technical Development to own the ADC capability build at the Wilton, UK site. This role leads conjugation chemistry, analytics, and cytotoxic payload facilities in a hands-on, leadership capacity.

The position requires a PhD and 8–10+ years in conjugation/CMC leadership, with cross-functional and cross-border collaboration. Based at Wilton, you will help drive platform commercialization and represent Vector externally at clients and industry

Qualifications

• PhD in chemistry, biochemistry, or a related discipline.
• 8–10+ years of post-PhD experience, including senior technical leadership.
• Experience owning a conjugation or bioconjugation platform build and ADC CMC.
• Experience with cytotoxic payload facility operations and SOP ownership.

Responsibilities

• Own the ADC capability build, including the linker portfolio, site-specific conjugation chemistry, and supporting HIC, CEX, and LC-MS analytics.
• Direct DAR (drug-to-antibody ratio) determination and peptide mapping workstreams in support of ADC characterization.
• Build and operate cytotoxic payload facilities, including authorship and ownership of SOPs and QC release specifications.
• Manage the cellular pharmacology technical partnerships.
• Lead Phase 4 commercialization of the ADC platform across Vector's four client tiers.
• Partner with the Chief Scientific Officer on the broader Technical Development strategy and roadmap.
• Represent Vector's ADC capability externally with clients, partners, and at industry conferences.

Skills

ADC Conjugation Leadership

Cross-functional Leadership

Cross-border Collaboration

Platform Build Experience

Antibody Engineering

Education

PhD in Chemistry, Biochemistry, or related

Tools

LC-MS

HIC

CEX

SOP Development

QC Release

Job description

Vector Laboratories is seeking a Senior Director/AVP, Technical Development to own the ADC capability build at the Wilton, UK site. This role leads conjugation chemistry, analytics, and cytotoxic payload facilities in a hands-on, leadership capacity.

The position requires a PhD and 8–10+ years in conjugation/CMC leadership, with cross-functional and cross-border collaboration. Based at Wilton, you will help drive platform commercialization and represent Vector externally at clients and industry