Senior Biostatistician — Lead Statistics & Global Trials

MMS; Greater London; On-site; GBP 65,000 - 110,000; Full time

Job summary

MMS Holdings is seeking a Senior Biostatistician in London to drive statistically rigorous analyses across Phase 1–4 trials. You will develop SAPs, TLFs, and integrate with sponsor teams while ensuring quality and regulatory compliance.

The role requires strong SAS skills, expertise in CDISC standards, and the ability to guide junior statisticians within a collaborative CRO environment. Excellent scientific writing is essential.

Qualifications

• Advanced knowledge of statistical methods and drug development processes.
• Strong SAS programming and macros experience.
• Experience with regulatory submissions (CDISC SDTM/ADaM) is preferred.
• Excellent scientific writing and communication skills.
• Willingness to guide junior biostatisticians.

Responsibilities

• Create SAPs and TLFs for multiple phases; collaborate with sponsor and teams.
• Review ADAM/TLFs and resolve comments with clients and programmers.
• Perform sample size calculations and provide high-quality analyses.
• Lead projects and manage client meetings, CRMs, and collaborations with regulatory and PMs.
• Prepare statistical sections of CSR with medical writers support.
• Ensure compliance with 21 CFR Part 11, FDA, and GCP.

Skills

SAS programming

CDISC SDTM/ADaM

Statistical analysis

MS Office

Communication

Education

Master's or PhD in Biostatistics/Statistics/Mathematics

Bachelor's degree in Biostatistics/Statistics/Mathematics

Tools

SAS Macro

Job description

MMS Holdings is seeking a Senior Biostatistician in London to drive statistically rigorous analyses across Phase 1–4 trials. You will develop SAPs, TLFs, and integrate with sponsor teams while ensuring quality and regulatory compliance.

The role requires strong SAS skills, expertise in CDISC standards, and the ability to guide junior statisticians within a collaborative CRO environment. Excellent scientific writing is essential.