Senior Analytical Data Science Programmer — Clinical Trials

Roche Holding AG; Welwyn Hatfield; On-site; GBP 65,000 - 90,000; Full time

Job summary

Roche Products Ltd. in Welwyn is seeking an Analytical Data Science Programmer to transform statistical analysis plans into high-quality, traceable programming outputs for clinical studies.

This role involves creating SDTM/ADaM datasets, tables, listings, figures, and interactive dashboards in a regulated environment. You will collaborate with biostatistics, data management and clinical operations to support regulatory submissions and generate data-driven insights, while upholding Roche

Qualifications

• Degree in statistics, computer science, mathematics or life sciences.
• Proficient in SAS or R and related statistical programming techniques.
• Experience with CDISC SDTM/ADaM standards is preferred.
• Experience delivering programming outputs in a regulated clinical environment.
• Strong documentation and audit trail practices.

Responsibilities

• Develop, validate, and maintain SDTM/ADaM datasets and TLFs for clinical trials.
• Translate analysis plans into executable, traceable programs meeting regulatory standards.
• Support regulatory submissions and generate data insights via dashboards.
• Collaborate with biostatistics, data management and clinical operations across studies.
• Lead programming deliverables for assigned studies and coordinate with partners.
• Interpret statistical analysis plans into reproducible specifications.
• Troubleshoot programming issues with limited supervision and manage risks.
• Contribute to standard macros and reusable components for efficiency.
• Document workflows and maintain audit trails for inspection readiness.
• Participate in cross-functional meetings to define timelines and deliverables.
• Engage in process improvement and ongoing learning in clinical programming.

Skills

SAS

R

Statistical programming

Data visualization

Clinical data standards

English fluency

Education

Bachelor/Master in Statistics/CS/Math/Life Sciences

Tools

SAS

R

Data visualization tools

Job description

Roche Products Ltd. in Welwyn is seeking an Analytical Data Science Programmer to transform statistical analysis plans into high-quality, traceable programming outputs for clinical studies.

This role involves creating SDTM/ADaM datasets, tables, listings, figures, and interactive dashboards in a regulated environment. You will collaborate with biostatistics, data management and clinical operations to support regulatory submissions and generate data-driven insights, while upholding Roche