Scientist - Infectious Diseases

Immunocore; Oxford; On-site; GBP 32,000 - 52,000; Full time

Job summary

Immunocore in Oxford, UK, seeks a Research Scientist to contribute to cross-functional efforts applying ImmTAX platform toward discovery of treatments for chronic infections such as HIV, HBV, and EBV. You will plan, execute experiments, analyze data, and support project progression in a matrixed team.

The role requires a PhD in a relevant field (or MSc/BSc with strong bench experience) and hands-on experience with cell culture, flow cytometry, ELISpot/ELISA, and molecular biology techniques.

Qualifications

• PhD in virology, immunology, cell biology, molecular biology, genomics or related discipline.
• 0–2 years of related experience in a bench-based laboratory.
• Alternatively, a BSc or MSc with significant work experience in relevant scientific areas.
• Proficient in culturing primary cells and cell lines.
• Flow cytometry, ELISpot and/or ELISA experience.

Responsibilities

• Plan, design and execute assignments to meet project goals within defined timeframes.
• Execute experiments addressing key scientific questions to enable project progression.
• Utilize cellular and molecular techniques including cell culture, flow cytometry, ELISpots, ELISAs, PCR/qPCR, Next-Gen sequencing.
• Analyze data, interpret results and make recommendations.
• Expand scientific knowledge through literature reviews and seminars.
• Collaborate within a matrixed team and present results at internal meetings.

Skills

Flow cytometry

ELISpot

ELISA

Cell culture

Molecular biology techniques

Education

PhD in virology/immunology/cell biology/genomics or related

BSc/MSc with significant bench experience

Job description

Location of role

Oxford, UK

Department

Infectious Diseases

Key Responsibilities

This position will contribute towards cross functional efforts focused on applying the ImmTAX® platform or other modalities for the development of novel treatments for diseases associated with chronic infections, including HIV, HBV, EBV and potentially other pathogens. The team is involved in multiple stages of the drug discovery and development process, from target discovery to clinical.

The purpose of the role is also to plan, design and execute experimental investigations with guidance from manager to support the advancement of the Company pipeline, process, or technology capabilities.

• With instruction and guidance from manager - plan, design, and execute assignments to meet project goals within defined timeframes
• Execute experiments to address key scientific questions and enable project progression, utilizing range of cellular and molecular techniques including some of the following:
• cell culture, flow cytometry, ELISpots, ELISAs, PCR/DD-PCR/qPCR, Next-Gen sequencing
• Some work will be conducted in a containment level 3 (CL3 facility) and will require handling of human viruses
• Analyse data, interpret results, and make recommendations
• Proactively expand scientific/technical knowledge in relevant fields including HIV/HBV/EBV related disease biology and drug development through review of scientific literature/ conference updates, peer to peer mentoring, and attendance at seminars/conferences in line with company strategy
• Work effectively in a matrixed team structure, as part of cross functional teams
• Participate and present results at internal meetings
• Establish relationships and possible collaborations within and outside of the company

Education, Experience and Knowledge

Essential Qualifications:

• PhD in virology, immunology, cell biology, molecular biology, genomics or related discipline and 0-2 years related experience
• Alternatively, a BSc or MSc with significant work experience in relevant scientific areas
• Worked in a bench-based laboratory environment and proficient in the following key techniques:
• Culturing primary cells and cell lines
• Flow cytometry
• ELISpot and/or ELISA

Preferred Qualifications:

• Knowledge/expertise of Immunology/HIV/HBV/EBV/other chronic infections
• Basic molecular techniques including PCR, molecular cloning, gel electrophoresis, site directed mutagenesis,
• Droplet Digital PCR/qPCR
• NextGen sequencing/Genomics/Transcriptomics

About the Company

Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industry’s most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions.

Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases.

At Immunocore, we recognize that our employees are our greatest asset. We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE represents more than just letters; it embodies our shared identity and drives our mission. We are dedicated to developing breakthrough therapies that transform patients’ lives, advancing medicine, and supporting one another in these pursuits.

Immunocore is proud to be an equal opportunity employer. As such, we are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law.