Scientist, In vitro DMPK

Pharmaron; Hoddesdon; On-site; GBP 32,000 - 52,000; Full time

Job summary

Pharmaron in Hoddesdon is seeking a Scientist to join the In Vitro DMPK Assay group, supporting discovery ADME screening through early development. You will work on in vitro DMPK methods and contribute to multi-disciplinary teams.

The role requires MSc or BSc in Biochemistry or biology, and practical lab experience. Strong collaboration and communication skills, plus knowledge of enzyme kinetics and cell culture, are desirable.

Qualifications

• MSc or BSc in Biochemistry, Biology or relevant subject.
• Practical laboratory experience gained during studies or industrial placement is desirable
• Proven ability to collaborate effectively in multi-disciplinary scientific teams.
• Excellent verbal and written communication skills.
• Excellent interpersonal skills with the ability to build strong working relationships with stakeholders and customers
• Understanding of enzyme kinetics
• Experience of liquid handling systems
• Cell culture skills, including both immortalised and primary cells
• Understanding of physicochemical properties of molecules

Responsibilities

• Follow and understand in vitro DMPK laboratory methods to answer project questions.
• Effectively work as part of multi-disciplinary teams to deliver agreed project requirements.
• Work with others to contribute with data and laboratory skills under the guidance, supervision and mentorship of others.
• Report and document results of experiments in line with department practices and governing policies, including reporting to support IND applications.
• Act as a system owner of equipment and instrumentation if required
• Implement and adoption of key internal business practices and applicable external regulations (e.g. Human Tissue Act), and adhere to all policies governing business activities.
• Support and positively contribute to departmental or site audits as directed by scientific supervisor / Line Manager as necessary.

Skills

Collaboration in multi-disciplinary"

Verbal and written communication

Interpersonal skills

Enzyme kinetics

Physicochemical properties of Molecule

Liquid handling systems

Cell culture skills

Biochemistry basics

Education

MSc or BSc in Biochemistry or Biology

Tools

Liquid handling systems

Cell culture equipment

Job description

Pharmaron is a global CRO helping pharma and biotech companies bring new therapies to life. With over 21,000 employees worldwide across 23 locations in the US, UK and China, we support drug discovery through to manufacturing with fully integrated, high-quality services.

We’re proud of the impact we make and just last year, we supported over 780 discovery projects, 1,000+ CMC programmes, and 1,000+ clinical trials across all phases. Our teams are involved in everything from small molecules to biologics and gene therapies, and we work with more than 3,000 global customers. To learn more, visit www.pharmaron.com .

About the Role

We are looking for Scientist to join our In Vitro DMPK Assay group at our Hoddesdon site supporting Discovery ADME screening through to early development (e.g. studies associated with ICHM12).

Key Responsibilities

• Follow and understand in vitro DMPK laboratory methods to answer project questions.
• Effectively work as part of multi-disciplinary teams to deliver agreed project requirements.
• Work with others to contribute with data and laboratory skills under the guidance, supervision and mentorship of others.
• Report and document results of experiments in line with department practices and governing policies, including reporting to support IND applications.
• Act as a system owner of equipment and instrumentation if required
• Implement and adoption of key internal business practices and applicable external regulations (e.g. Human Tissue Act), and adhere to all policies governing business activities.
• Support and positively contribute to departmental or site audits as directed by scientific supervisor / Line Manager as necessary.

Candidate Profile

• MSc or BSc in Biochemistry, Biology or relevant subject
• Practical laboratory experience gained during your studies or an industrial placement is desirable
• Proven ability to collaborate effectively in multi-disciplinary scientific teams.
• Excellent verbal and written communication skills.
• Excellent interpersonal skills with the ability to build strong working relationships with stakeholders and customers
• Understanding of enzyme kinetics
• Experience of liquid handling systems
• Cell culture skills, including both immortalised and primary cells
• Understanding of physicochemical properties of molecules

Why Pharmaron?

Collaborative Culture: Thrive in our inclusive and collaborative environment, where teamwork and innovation go hand in hand. Here, your voice matters, and your contributions make a real impact. "Employees Number One" and "Clients Centered" are the core cultural values at Pharmaron. Our culture, which sets Pharmaron apart from other organizations, has evolved from our deep commitment to our employees, partners and collaborators.

Pharmaron is a premier service provider for the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities and established a broad spectrum of research, development, and manufacturing service capabilities throughout the entire drug discovery, preclinical, and clinical development process across multiple therapeutic modalities, including small molecules, biologics, and CGT products. With over 21,000 employees and operations in the U.S., the U.K. and China. Pharmaron has an excellent track record in delivering R&D solutions to its partners in North America, Europe, Japan, and China.

• Job Category Scientific (Metabolism (Met-id))