Scientist 2 - Analytical

Centre for Process Innovation Limited; Tees Valley; On-site; GBP 30,000 - 45,000; Full time

Job summary

A leading biopharmaceutical organization in Tees Valley seeks an experienced scientist to join their analytical team. The role involves supporting innovative biopharmaceutical projects, including mRNA vaccines and monoclonal antibodies, utilizing advanced analytical techniques. Candidates should have a Foundation Degree in a relevant field and expertise in characterizing biologics. The position offers opportunities for development within a collaborative environment and comes with extensive benefits, including up to 36 days of leave and life insurance.

Benefits

Up to 36 days holiday

Life assurance and accident insurance schemes

Qualifications

• Experienced in techniques like UPLC/HPLC, mass spectrometry, and biolayer interferometry.
• Understanding of GMP and/or Data Integrity principles is required.
• Ability to work independently and collaboratively across multidisciplinary teams.

Responsibilities

• Interpreting and reporting on experimental data to stakeholders.
• Maintaining GMP and Data Integrity compliance.
• Supporting business development through technical input.

Skills

Analytical techniques for biologics characterisation

High performance liquid chromatography (UPLC/HPLC)

Mass spectrometry

Data presentation and documentation

Problem-solving

Education

HNC/Foundation Degree in Scientific/Engineering discipline

Tools

Science software tools

Job description

CPI helps make great ideas and inventions areality. We’re ateam of intelligent people using advances in science and technology to solve the biggest global challenges in healthcare and sustainability.

Through our incredible people and innovation infrastructure, we collaborate with our partners in industry, academia, government, and the investment community to accelerate the development and commercialisation of innovative products.

From health technologies and pharmaceuticals to sustainable food and materials innovations, we turn the entrepreneurial spirit and radical thinking of our people and partners into incredible impact that makes our world abetter place.

Why this role is important for CPI’swork

CPI has an exciting opportunity for an experienced scientist to join its dynamic, analytical team within the national biologics manufacturing centre in Darlington to support cutting-edge biopharmaceutical innovation across platforms including mRNA vaccines, AAV vectors, monoclonal antibodies, and recombinant proteins.

This role offers the opportunity to contribute to impactful projects such as Fortuna 5 ( AAV ) and Electra (protein), applying analytical expertise to characterise complex biologics and support process development. It is also offers the chance to work across avariety of analytical techniques, some of which may include: high performance liquid chromatography ( UPLC / HPLC ), mass spectrometry, capillary isoelectric focussing, biolayer interferometry, dynamic light scattering, differential scanning calorimetry, circular dichroism, capillary electrophoresis, ELISA , polymerase chain reaction techniques (qPCR and ddPCR), microfluidic imaging, SEC-MALS and SDS-PAGE .

The Role

Key tasks in the role will include (but are not limited to the below), please download the job description for full details available on the CPI careers page :

• Interpreting and reporting on experimental data to internal and external stakeholders
• Maintaining GMP and Data Integrity compliance across all analytical activities
• Supporting business development through technical input and client engagement
• Collaborating across teams to deliver project milestones and continuous improvement
• Providing mentoring and training to junior team members
• Maintaining and calibrating analytical equipment to ensure operational readiness

The successful candidate will have the opportunity to support avariety of projects, where analytical work packages can include:

• Designing, verifying, and applying analytical methods for biopharmaceutical characterisation
• Monitoring residuals and impurities, to support bioprocess development (e.g. host-cell proteins, residual DNA , RNA , and endotoxins)
• Molecule characterisation to Identify critical quality attributes and molecule heterogeneity
• Investigate stability (e.g. fragmentation, aggregation, solubility, particle formation)
• Accelerated stability/forced degradation studies
• Understand degradation pathways
• Develop stability indicating assays
• Identify critical quality attributes

The person we are seeking

The Person

The successful candidate will be educated to aminimum of HNC /Foundation Degree level (or equivalent) in aScientific/Engineering discipline with industrial experience and;

• Be experienced in analytical techniques for biologics characterisation and problem-solving in some of the following techniques: high performance liquid chromatography ( UPLC / HPLC ), mass spectrometry, capillary isoelectric focussing, biolayer interferometry, dynamic light scattering, differential scanning calorimetry, circular dichroism, capillary electrophoresis, ELISA , polymerase chain reaction techniques (qPCR and ddPCR), microfluidic imaging, SEC-MALS and SDS-PAGE
• Have an understanding of GMP and/or Data Integrity principles
• Be able to demonstrate the ability to work independently and collaboratively across multidisciplinary teams
• Be an effective communicator with experience in data presentation and documentation

It would be great if you had one or more of the following:

• Membership of arelevant professional body
• Experience mentoring or training others
• Familiarity with statistical analysis, QbD/DoE and application to experimental design, and scientific softwaretools
• Familiarity with high-throughput screening using automated liquid handling systems.

What does CPI offeryou?

At CPI , we offer awide range of benefits to our employees, this includes:

• Up to 36 days holiday, including bank holidays – Plus aholiday purchasing scheme
• Life assurance and accident insurance schemes

CPI is an organisation based in the UK . Commencement of employment is conditional to demonstrating right to work in the UK , sponsorship may be available.