Research Technician - UOD2452

University of Dundee; Dundee; On-site; GBP 26,000 - 34,000; Full time

Job summary

The University of Dundee's Lee Lab seeks a Research Technician to support malaria parasite research, including CRISPR editing, sequencing, and data analysis. The role involves working with barcoded parasite lines and MinION sequencing to profile compounds and resistance profiles.

Ideal candidates will have experience in parasite or cell culture and bioinformatics, and collaborate with internal and external partners. Strong communication and organizational skills are essential for success.

Qualifications

• Degree in a relevant field.
• Experience with cell culture.
• Experience in bioinformatics.
• Experience with genetic modification.
• Excellent written and oral communication skills.

Responsibilities

• Conduct research to investigate modes of action of antimalarial compounds.
• Perform next-generation sequencing and data analysis.
• Coordinate compound and sample management.
• Collaborate and communicate with multiple research groups.

Skills

Cell culture

Bioinformatics

CRISPR editing

Data analysis

Communication skills

Education

Degree in a relevant field

Tools

MinION sequencing

Job description

Lee Lab investigates the molecular basis of drug resistance in

Plasmodium falciparum, the human malaria parasite, working to uncover the mechanisms that allow the parasite to evade treatment. Using cutting-edge molecular genetics tools, including CRISPR/Cas approaches, the lab aims to identify new therapeutic targets and develop platforms to profile antimalarial compounds and their resistance profiles. As members of the Gates Foundation-funded Malaria Drug Accelerator (MalDA) Consortium, the lab collaborates internationally to accelerate the discovery of the next generation of antimalarial drugs.

About the Faculty of Life Sciences

The Faculty of Life Sciences is internationally recognised for world-leading research in biological and biomedical sciences. Our work explores the molecular and cellular mechanisms underpinning health and disease, with impact across human, animal and environmental systems.

We are home to a collaborative community of over 600 academic and professional services staff and more than 100 doctoral researchers, supported by high-quality facilities and a culture that promotes innovation, integrity and inclusion.

Our research-led teaching supports undergraduate and postgraduate students, equipping them with the knowledge and skills for future careers. We also have a strong track record of translating research into real-world impact, including successful spin-out companies.

About the Role

An opportunity is available for a motivated

Research Technician to join the Lee team, supporting our work to identify and understand the mode-of-action of antimalarial compounds. The goal is to optimise drug profiling assays using libraries of barcoded parasite lines, use these assays to profile antimalarial collections, as well as construct additional transgenic parasite lines using CRIPSR editing to expand the parasite screening library. The role spans both experimental and computational work, including minION-based amplicon sequencing and data analysis. The ideal candidate will have expertise in parasite or cell culture, as well as experience with bioinformatics. The successful candidate will communicate effectively with a range of internal and external collaborators. Excellent communication and organisational skills, and an enjoyment of collaborative working, are essential

For further information about this position please contact

Prof. Marcus Lee at [e-mail]

Key Responsibilities

You will be responsible for:

• Conducting research to investigate the modes of action of antimalarial compounds
• Performing next-generation sequencing and data analysis
• Coordinating compound and sample management
• Collaborating and communicating with multiple research groups

Who We're Looking For

The ideal candidate will have:

• Degree in a relevant field
• Experience with cell culture
• Experience in bioinformatics
• Experience with genetic modification
• Excellent written and oral communication skills, including excellent interpersonal skills

Why Join the University of Dundee

At the University of Dundee, we are driven by a clear purpose: to transform lives through education, research and innovation.

We are internationally recognised for the real-world impact of our work, particularly in areas such as life sciences, health and engineering. Our collaborative and inclusive culture brings together talented people from across disciplines to tackle global challenges and deliver meaningful change.

Located in the vibrant city of Dundee, our campus offers a supportive and forward-looking environment where colleagues are empowered to develop, contribute and succeed.

Find out more about working at the University of Dundee: