Research Fellow, Medicinal Chemistry

Vertex Pharmaceuticals; Oxford; On-site; GBP 120,000 - 180,000; Full time

Job summary

Vertex Pharmaceuticals is seeking an outstanding Chemistry Research Fellow (Director level) to lead small molecule design across projects and drive best practice in medicinal chemistry, including applying AI methodologies to key challenges.

The role emphasizes leadership, publication and patent coordination, and developing team capabilities while maintaining highest data integrity within a fast-moving drug discovery program at Vertex.

Qualifications

• Demonstrates leadership in chemistry
• Leads molecular design with sound judgment and methodology
• Mentors team members in medicinal chemistry
• Understands the small molecule drug discovery process
• Drives data integrity and provides interpretations to project teams

Responsibilities

• Demonstrates chemistry leadership across projects
• Leads design efforts of small molecule targets
• Coordinates publications and patent submissions
• Drives AI methodologies in small molecule drug discovery
• Ensures highest data integrity and rigorous decision making

Skills

Chemistry leadership

Molecular design

Mentoring

Drug discovery

AI in drug discovery

Education

Ph.D. in chemistry or related science

Masters in chemistry or related science

Bachelors in chemistry or related science

Job description

General Summary

We are seeking an outstanding medicinal chemist to join our team as a Chemistry Research Fellow (Director level). The ideal candidate has an impressive history of accomplishments which have contributed significantly to the advancement of projects and is recognized as a thought leader and an acknowledged expert in medicinal chemistry. Responsibilities will include leading the design efforts of small molecule targets across a project and driving best design practice across our portfolio of projects, including application of cutting-edge AI methodologies to key medicinal chemistry challenges.

Job Description

We are seeking an outstanding medicinal chemist to join our team as a Chemistry Research Fellow (Director level). The ideal candidate has an impressive history of accomplishments which have contributed significantly to the advancement of projects and is recognized as a thought leader and an acknowledged expert in medicinal chemistry. Responsibilities will include leading the design efforts of small molecule targets across a project and driving best design practice across our portfolio of projects, including application of cutting-edge AI methodologies to key medicinal chemistry challenges.

Key Requirements And Responsibilities

• Demonstrates intellectual and/or technological chemistry leadership
• Leads our science around molecular design, combining sound judgment, strong initiative and thorough methodology
• Helps to teach and develop employees throughout the group in the field of medicinal chemistry.
• Has a deep and thorough understanding of the small molecule drug discovery process.
• Drives the highest standards of data integrity and provides interpretations and recommendations to Project Teams
• Coordinates publication and patent submissions
• Will drive best practice in AI methodologies applied to small molecule drug discovery

Education And Experience

• Ph.D. (or equivalent degree) in chemistry or related science and relevant post-doctoral employment experience, or
• Masters Degree (or equivalent degree) in chemistry or related science and relevant employment experience, or
• Bachelors Degree (or equivalent degree) in chemistry or related science and relevant employment experience

At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.

Flex Designation

On-Site Designated

Flex Eligibility Status

In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [e-mail]