Research Fellow - Development of Therapeutics

University of South Hampton; Southampton; On-site; GBP 30,000 - 45,000; Full time

Job summary

A leading university in the UK is seeking a highly motivated Research Fellow to join its Centre for Cancer Immunology. This role involves developing novel antibody-based therapeutics and requires a PhD-equivalent background in immunology. The successful candidate will contribute to significant clinical research aimed at tackling cancer and autoimmune diseases. The position is available for two years, with an anticipated extension based on funding availability.

Qualifications

• High-quality publications related to immunology or antibodies.
• Experience with mouse disease models is desirable.
• Good IT skills are required.

Responsibilities

• Understand fundamental biological processes for therapeutic development.
• Generate engineered antibodies for cancer and autoimmune diseases.
• Contribute to interdisciplinary research programs.

Skills

Cellular techniques related to immunology

Flow cytometry

Fluorescence microscopy

In vitro cellular assays

Education

PhD equivalent in relevant field

Job description

Research Fellow - Development of Therapeutics

The position will be held in the Centre for Cancer Immunology at Southampton General Hospital. This Centre builds on a 40-year history of pioneering immunology and cancer research at Southampton and represents the first dedicated cancer immunology centre in the UK. The activities in this centre span from pioneering discovery science to applied research and preclinical modelling and, crucially, onto first-in-human clinical trials and beyond. The centre houses world-class research facilities, including state-of-the-art scientific laboratories and a clinical trials unit.

The position is associated with the laboratory of Professors Ward and Ober. Their interdisciplinary research program is dedicated to the development of novel antibody-based therapeutics that has led to several therapeutics that are currently in late-stage clinical trials or approved. The group also develops advanced microscopy techniques for the evaluation of novel therapeutics in cellular environments. Their research is supported by major grants from the Wellcome Trust, Cancer Research UK and support from collaborating biopharma companies.

The appointee will be highly motivated and excited by the challenges involved in using mechanistic approaches to understand fundamental biological processes, with the goal of using this information to generate engineered antibodies for use as therapeutics in cancer and autoimmune disease. The appointee is expected to have an outstanding background, including high quality publications, in cellular techniques related to immunology and/or antibodies, including flow cytometry, fluorescence microscopy and other in vitro cellular assays. Experience in using mouse disease models is also desirable.

Scientific knowledge in the areas described above equivalent to PhD* level is required. The post-holder will possess relevant academic qualifications and work experience as well as good IT skills. Non-UK citizens are also welcome to apply.

The position is initially for two years. Availability of funds for a period beyond the two-year timeframe is anticipated.

We are committed to equality, diversity and inclusion and welcome applicants who support our mission of inclusivity.

Apply by 11.59 pm GMT on the closing date. For assistance contact Recruitment on [phone] or [e-mail] quoting the job number.