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UK Dementia Research Institute (UK DRI) invites a technical leader to design and build software that maps scientific questions, claims, and evidence across Alzheimer’s research. You will lead ingestion pipelines, create inspectable graphs, and connect publications with datasets to enable collaboration and reproducible science.
You will join as a founding member of our AI initiative, shaping Lab Brains and scientific workflows.
Interviews: There will be a two-stage process comprising of an online interview and an in-person interview.
In-person interview: 3rd December 2026
Closing date for applications: 15th November 2026
The UK Dementia Research Institute (UK DRI) is a globally leading multidisciplinary research institute with a community of c. 1000 researchers investigating the spectrum of neurodegenerative disorders causing dementia, driving a step change in our understanding of neurodegeneration, and accelerating the discovery, development and delivery of interventions that will help diagnose, treat, and ultimately prevent dementia.
Research produces papers, datasets and promising ideas, but the connections between them are difficult to maintain. A finding may depend on an untested assumption. Two apparent contradictions may concern different experimental systems. Several labs may be blocked by the same missing capability. Important negative results and developing work may never become visible outside the team that produced them.
Help UK DRI understand what is known, where the evidence disagrees and what work could make the biggest difference next. You can learn more about our ambitions here.
You will develop the strategy and build software that makes these questions easier to investigate and act on. Starting with a focused Alzheimer’s disease research question, you will help scientists create and maintain an inspectable map of claims, evidence, disagreements, capabilities and possible routes towards a meaningful outcome. Over time, that work should connect published literature with selected, authorised unpublished research and the knowledge held across UK DRI laboratories.
We are looking for a technical leader who thinks big and cares about how science establishes knowledge and how institutions help people learn and work together. You might already be interested in discourse graphs, claims and evidence, outcome graphs, reproducibility, open science or new ways of organising research. You might have encountered the same problems while building search tools, scientific data systems or collaborative software. We value the ability to turn that curiosity and ability to think big into useful working systems.
You will be a founding member of the UK DRI AI initiative, working as a peer with an engineer building Lab Brains and scientific workflows. Together, you will connect what laboratories learn and influence what the institute can understand and do.
Build with scientists and methodologists, combining software development with focused scientific review. Help reviewers make disagreement explicit and productive. Design the workflow so that maintaining the shared account requires less effort than reconstructing it repeatedly.
Lead on system evaluation against ordinary search and structured evidence review on the same questions and sources. Measure evidence quality, scope errors, review effort, correction and whether the work improves a real decision or hand-off. Preserve failed ideas, alternative interpretations and justified no-action decisions.
Reproducibility is central: a reader should be able to inspect the source and analysis behind a claim, understand its limitations and see what changed. Laboratory owners retain control over what is shared. Scientific and programme decisions remain with accountable people, supported by the software you build.
Influence how senior management embraces AI across the Institute to deliver its mission faster.
First month: agree one scientific question and intended outcome with named reviewers; define a small source corpus and a baseline; build an inspectable first representation of evidence and uncertainty.
By three months: deliver a reviewed claim-and-evidence view and an initial outcome map that scientists can correct, including an explicit disagreement or unresolved assumption and a documented next decision.
By six months: connect the map to an approved lab or institutional workflow, test a proposed capability hand-off or scientific follow-up, and show what the system adds beyond simpler retrieval and manual review.
By twelve months: maintain the scoped resource as evidence changes, demonstrate a documented decision/action/result feedback loop, and deliver an implementation strategy for reusable software, evaluation methods and present a justified plan for further field coverage to senior management.
We believe in rewarding our team with more than just a competitive base salary an opportunity to make a difference. Here’s what you can look forward to:
The UK DRI embraces diversity, inclusion and accessibility for all of our people. We are committed to building a diverse organisation that represents the communities we serve and ensuring inclusion in everything we do. This means ensuring our recruitment processes are barrier-free and as inclusive as possible to everyone. We will make adjustments for people who have a disability or long-term condition.
By applying to this role, you understand and agree that your information will be shared within the UK DRI People & Culture team and/or any team members who will be part of the hiring process.