Research Associate: Ubiquitin Signalling & Nanobody Tools

University of Manchester; Manchester; Hybrid; GBP 34,000 - 42,000; Full time

Benefits offered by this job

Fantastic pension scheme

Employee health and wellbeing services

Excellent annual leave entitlement

Bank holidays

Discounts at major retailers

Job summary

The University of Manchester's Kulathu group invites applications for a postdoctoral Research Associate with a background in protein biochemistry, molecular biology or molecular recognition. You will join a sociable multidisciplinary team led by Professor Yogesh Kulathu to study how ubiquitin signalling encodes cellular outcomes and to develop tools for disrupting or visualising these processes.

Responsibilities include developing nanobody tools, performing quantitative binding assays, and

Qualifications

• It is required to have experience in protein biochemistry or molecular biology with interest in ubiquitin signalling.
• Experience with protein engineering or studying protein–protein interactions is advantageous.
• Cellular imaging experience would be beneficial.

Responsibilities

• Develop a nanobody toolkit to recognise polyubiquitin chains and enable new experiments.
• Support a BBSRC-funded programme studying how ubiquitin signals control cellular outcomes.
• Collaborate with structural biology, proteomics and cell biology teams.

Skills

Protein biochemistry

Molecular biology

Molecular recognition

Job description

The University of Manchester's Kulathu group invites applications for a postdoctoral Research Associate with a background in protein biochemistry, molecular biology or molecular recognition. You will join a sociable multidisciplinary team led by Professor Yogesh Kulathu to study how ubiquitin signalling encodes cellular outcomes and to develop tools for disrupting or visualising these processes.

Responsibilities include developing nanobody tools, performing quantitative binding assays, and