Research Associate in Secondary Ion Mass Spectrometry (10401)

Rosalind Franklin Institute; East Hagbourne; Presencial; GBP 33.750 - 41.250; Jornada completa

Ventajas ofrecidas por este puesto de trabajo

25 days holidays

Generous pension scheme

Group Life Assurance

Hybrid and flexible working

Training and development opportunities

Perkbox access

Free on-site parking

Descripción de la vacante

The Rosalind Franklin Institute is seeking a Research Associate to advance mass spectrometry imaging, focusing on SIMS modalities for near-cellular resolution in tissue samples. You will work with cutting-edge instrumentation and collaborate across biological and MS teams to push the boundaries of chemical imaging.

You will design experiments, contribute to outputs such as papers and patents, and supervise students or visitors while developing scientific independence within a dynamic,

Formación

• PhD/DPhil required or submitted; initial appointment at £37,500 with uplift on qualification.
• Experience developing SIMS modalities for high-sensitivity, high-resolution imaging.
• Ability to plan and conduct experiments and supervise students/visitors.

Responsabilidades

• Develop new SIMS modalities for enhanced sensitivity and spatial resolution.
• Collaborate with biological and MS experts to optimise MSI conditions.
• Design, model and construct modalities for subcellular chemical imaging.
• Lead outputs such as papers and patents and supervise junior researchers.

Conocimientos

Mass spectrometry (SIMS)

Experiment design

Collaboration

Research independence

Educación

PhD/DPhil (or submitted)

Herramientas

MS instrumentation

Descripción del empleo

The Rosalind Franklin Institute (the Franklin) is a technology institute established by the UK Government as a unique centre committed to advancing tools that are needed to transform healthcare in the future.

The Institute brings together researchers in life and physical sciences, and engineering, to develop a spectrum of tools which we will use to image, interpret and intervene in biological systems. These insights will speed up the discovery of new medicines, help find new diagnostics and contribute to a deeper understanding of human health and disease. Our Science Strategy seeks to focus the Franklin’s research and unite our researchers around our Technology Innovation Challenges and Life Science Challenges. For more information on the Franklin’s Challenges click here.

As part of the Integrated Chemical Imaging in Cells and Tissue Challenge, your role will be to develop mass spectrometry (MS) technologies that provide a comprehensive, spatially-resolved chemical view of whole tissues at near cellular resolution. Secondary ion mass spectrometry (SIMS) has the best in spatial resolution of imaging MS techniques, but there are still challenges in obtaining a holistic picture of the molecular makeup of cells at a subcellular level. This role will work with cutting edge instrumentation and further develop this instrumentation towards tackling this challenge.

As a Research Associate at the Franklin, you will bring scientific knowledge and skills to deliver a specific research project and/or you will bring independent, creative science, or specific skills to a team delivering a project or program. Through this work, you will build scientific independence, develop new science and leadership skills and establish a growing reputation externally.

Key Responsibilities

• Develop new SIMS modalities for advanced sensitivity and spacial resolution.
• Collaborate with biological and MS experts at the Franklin to optimise MSI conditions and methods for specific applications and challenges.
• Adapt to working across multi-modal instrumentation and collating multiomic and imaging data from diverse sources and scales.
• Investigate the use of cutting edge instrumentation to explore key scientific challenges such as sensitivity and spatial resolution.
• Design, model and construct new modalities to enable subcellular chemical imaging.
• Plan and conduct experiments, analyse and interpret results and supervised delivery of outputs (e.g. research report, patent application) in a scientific or technology area of interest.
• Work within a project team, contributing to wider projects around Franklin's key Challenges.
• Lead major contributions to outputs from research including papers, patents and both internal and external presentations.
• Support and develop others including day-to-day supervision of students or visitors in areas related to own research.
• Have supervised, staged progression to first stages of scientific independence with opportunities to further develop science and skills/experience.
• Enhance your research through collaboration with other researchers and make active contributions to exchanging of ideas through your own network.
• Be able to understand, interpret, create and communicate appropriately within a research context.
• Develop search and discovery skills and techniques.
• Be supervised by a Scientist/Senior Scientist in delivery of research outputs, either in the context of a project or Challenge or as an early career development fellow.

Whilst the role requires candidates to hold a PhD/DPhil (or equivalent), we may consider candidates who have submitted their PhD/DPhil thesis, in which case the initial appointment will be made at £37,500 per annum (to be increased on completion of the PhD/DPhil qualification).

Benefits

• 25 days holidays plus bank holidays and Christmas holiday shutdown
• Generous pension scheme (employer’s contribution currently up to 18%)
• Group Life Assurance (also known as Group Life Insurance or Death in Service)
• Buying and Selling Annual Leave
• Workplace Nursery Salary Sacrifice Scheme
• Hub building with state-of-the-art laboratories
• Hybrid and flexible working
• Training and development opportunities for staff at all levels
• Bus pass discount scheme and good transport links to Oxford and surrounding areas
• Cycle to Work Scheme
• Access to employee discount platform (Perkbox)
• Occupational Health and wellbeing support including Employee Assistance (24/7 support and counselling)
• Health Cash Plan
• Subsidised canteen and food outlets on campus
• Free on-site parking
• Campus location in beautiful countryside with social and sports clubs open to staff

Equality, Diversity & Inclusion

We are committed to creating an inclusive environment where every applicant has an equal opportunity to showcase their talents and abilities. This includes making adjustments for candidates with specific needs. Please contact us at [e-mail] to discuss your requirements confidentially.