Research Associate in Paediatric Cancer Drug Resistance

1000scholars; Cambridge; On-site; GBP 38,000 - 46,000; Full time

Job summary

The University of Cambridge invites applications for a post-doctoral scientist to join Professor Suzanne Turner’s group in the Department of Pathology. The project focuses on mechanisms of drug resistance in paediatric cancers and development of novel biomarkers for prognosis and therapy.

Ideal candidates will have a PhD in biological sciences, strong molecular biology skills including ChIP and sequencing, and experience supervising PhD students.

Qualifications

• PhD in biological sciences is required.
• Experience with chromatin immunoprecipitation (ChIP) and sequencing is essential.
• Experience supervising PhD students is preferred.
• Knowledge of cancer biology is desirable.

Responsibilities

• Investigate mechanisms of drug resistance in paediatric cancers.
• Develop and validate biomarkers for prognosis and therapy guidance.
• Supervise and mentor PhD students within the project.
• Publish findings and present at relevant conferences.

Skills

Molecular biology techniques

PhD supervision experience

Cancer biology knowledge

Education

PhD in Biological Sciences

Tools

ChIP sequencing

Job description

The University of Cambridge wishes to appoint a post-doctoral scientist to join the research group of Professor Suzanne Turner in the Department of Pathology. We are searching for a highly motivated scientist to investigate mechanisms of drug resistance in paediatric cancers.

Neuroblastoma is a rare childhood cancer of the peripheral nervous system that has a poor prognosis particularly for children diagnosed with high-grade disease. Our research seeks to understand why this is the case with a particular focus on drug resistance mechanisms and the development of novel biomarkers to identify poor prognosis patients. In particular, this project funded by the Little Princess Trust is looking at post-translational histone modifications towards novel therapeutic approaches and associated biomarkers towards clinical application.

The ideal candidate would have knowledge of cancer biology and experience of molecular biology techniques as well as experience in supervising PhD students.

Candidates must have a PhD in biological sciences, and a track record of research achievements. Knowledge of molecular biology techniques including chromatin immunoprecipitation and sequencing are essential. We seek collegiate applicants who are committed to fostering a positive and inclusive research culture.

Fixed-term: The post is available for 6 months (with the possibility of an extension) in the first instance with a negotiable starting date and subject to a 6-month probationary period.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

The Department of Pathology is a very active research and teaching department in the School of Biological Sciences. We offer modern laboratory spaces, flow cytometry, imaging, histology, proteomics and sequencing facilities in the centre of Cambridge. We host an external seminar series as well as internal talks, journal clubs, and a Departmental annual symposium. There are approximately 40 research groups spanning a wide array of disciplines, including infectious and genetic diseases, immunology and cancer biology. Additional information can be found at https://www.path.cam.ac.uk/research

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

£37,694 to £46,049 per annum