Research Assistant – Vlp Vaccine Development

University Of Oxford; Oxford; On-site; GBP 30,000 - 42,000; Full time

Job summary

University of Oxford’s Jenner Institute is seeking a Research Assistant in VLP Vaccine Development to join Associate Professor Sandy Douglas' group. The role focuses on manufacturing and analytics for viral vaccine platforms, with training across multiple projects and exposure to diverse techniques, including cell culture, protein production and purification.

You will produce high quality data, contribute to experimental design and analysis, and develop skills under senior supervision in a

Qualifications

• MSc in biological sciences, biochemistry or related discipline is essential.
• Practical biology or laboratory work experience is required.
• Knowledge of vaccinology and infectious diseases is essential.

Responsibilities

• Produce high quality data using modern lab techniques including cell culture, protein production and purification.
• Assist in multiple projects on viral vaccine manufacturing and analytical assay development.
• Contribute to experimental design, planning and analysis within existing research programs.

Skills

Mammalian cell culture

Recombinant protein production

ELISAs

Size exclusion chromatography

Viral neutralisation assays

Vaccinology knowledge

Infectious disease knowledge

Experimental design

Data analysis

Education

MSc in biological science, biochemistry or related discipline

Tools

Flow cytometry

Analytical size exclusion chromatography

Protein purification

Job description

We are seeking

to appoint a Research Assistant in VLP Vaccine Development to work with Associate Professor Sandy Douglas' group. This is a fantastic opportunity to work with a team of scientists developing vaccines and vaccine platforms, as well as advancing knowledge on a range of infections. The scope of the Douglas group's work covers pre-clinical development, vaccine manufacturing and clinical trial, and adenovirus genetic engineering. You will be mainly focused on manufacturing: the researcher will receive training and contribute to multiple projects on viral vaccine manufacturing and analytical assay development, particularly within a project on VLP vaccine platforms and EBV. You will have responsibility for producing high quality data using a range of modern laboratory techniques, such as cell culture, recombinant protein production and purification, flow cytometry and analytical size exclusion chromatography. You will develop your skills in experimental design, planning and analysis, while making a meaningful contribution to global health through developing new vaccines. You will be based at the Jenner Institute, Old Road Campus Research Building, Headington. You will have the opportunity to develop a diverse range of knowledge and skills. You will develop your career with mentoring from a senior team comprising Associate Prof. Sandy Douglas (the Group Leader), Dr Catherine Cherry (day-to-day supervisor), and members of the research team. The post would be particularly suited if you are enthusiastic about pursuing graduate studies in medical science, as the exposure to a range of projects and techniques will provide rich development opportunities. It is essential that you hold a MSc degree in biological science, biochemistry or a related discipline. Practical experience of biology, medical science or similar laboratory work is a must. You must have knowledge of vaccinology, infectious disease and molecular biology. It is essential that you have experience of mammalian cell culture, recombinant protein production, ELISAs, size exclusion chromatography and viral neutralisation assays. Ability to work within established research programmes, with the potential to contribute ideas for new and improved experiments is a must.