Research Assistant - INTERNAL ONLY

King's College London; City of Westminster; On-site; GBP 32,000 - 42,000; Full time

Benefits offered by this job

Professional development leave (10+8.5

Job summary

King's College London’s IoPPN invites applications for a Research Associate to contribute to neurological resilience research after inflammatory challenge in individuals at familial risk of MS. The role is based in the Department of Neuroimaging within IoPPN, under Prof.

Adam Hampshire, with duties spanning recruitment, data collection, cognitive/MRI analysis, and longitudinal study work. You will collaborate across the group, manage data and assist in publications, while communicating study

Qualifications

• BSc (or equivalent) in Medical Biosciences, Biomedical Sciences or Neurosciences.
• Laboratory experience in a project involving multiple sclerosis, with understanding of MS pathology or clinical research.
• Experience with molecular/cellular techniques: Western blotting, qPCR, proteomics, flow cytometry, tissue culture, IHC/IF, spatial transcriptomics.
• Knowledge of immunology/neuroimmunology or inflammatory mechanisms related to MS.
• Experience analyzing brain tissue sections or MRI data related to MS.
• Programming or data-analysis skills (R or MATLAB).
• Experience communicating risk and uncertainty to participants and families.
• Experience in a research environment with governance, confidentiality and meticulous data management.

Responsibilities

• Coordinate research assessments and support participant engagement and recruitment.
• Analyse existing cognitive and MRI datasets and contribute to longitudinal data collection.
• Contribute to data management, statistical analysis, and research presentations.
• Assist in preparation of publications and dissemination of findings.

Skills

MRI data analysis

R

MATLAB

Risk communication

Education

BSc in Medical Biosciences/Biomedical Sciences/Neurosciences

Tools

Western blotting

qPCR

Proteomics

Flow cytometry

Tissue Culture

IHC/IF

Spatial transcriptomics

Job description

This is an exciting opportunity for a research associate to contribute to research investigating neurological resilience, after an inflammatory challenge, in individuals with familial risk of multiple sclerosis (MS). The post holder will be based in the Department of Neuroimaging at the at the Institute of Psychiatry, Psychology and Neuroscience (IoPPN), one of the most esteemed clinical research centres worldwide, working under the guidance of Prof Adam Hampshire (Centre for Neuroimaging Sciences, IoPPN). The successful candidate will contribute to a programme of research using cognitive, neuroimaging and immune measures to investigate individual differences in response to transient inflammation. The role will involve supporting participant engagement and recruitment, coordinating research assessments, analysing existing cognitive and MRI datasets and contributing to the collection and analysis of longitudinal data before and after routine influenza vaccination/inflammatory challenge. The role will involve communicating study information and risk to participants and families. The post holder will work closely with researchers across the group and contribute to data management, statistical analysis, research presentations and preparation of publications. This is a full-time post (35 hours per week), and you will be offered a 6 month fixed term contract. Research staff at King's are entitled to at least 10 days per year (pro-rata) for professional development. This entitlement, from the Concordat to Support the , applies to Postdocs, Research Assistants, Research and Teaching Technicians, Teaching Fellows and AEP equivalent up to and including grade 7. Visit the for more information.

To be successful in this role, we are looking for candidates to have the following skills and experience:

Essential criteria

• BSc (or equivalent) in Medical Biosciences, Biomedical Sciences or Neurosciences.
• Practical laboratory research experience in a research project involving multiple sclerosis, with understanding of multiple sclerosis pathology, disease mechanisms or clinical research.
• Demonstrate experience with molecular and cellular laboratory techniques, including Western blotting, qPCR, Proteomics, Flow cytometry, Tissue Culture, IHC/IF and Spatial transcriptomics.
• A working knowledge of immunology, neuroimmunology or inflammatory mechanisms relevant to multiple sclerosis.
• Previous experience analysing brain tissue sections or MRI data to investigate brain pathology and structural changes associated with multiple sclerosis specifically.
• Programming or data-analysis skills (E.g., R or MATLAB).
• Previous experience in a patient-facing or clinical research role in which communicating risk and uncertainty appropriately to participants and families was an important responsibility.
• Previous experience working in a research environment with an understanding of research ethics, governance, confidentiality and data protection, and maintenance of accurate laboratory records, sample tracking and research documentation.

Desirable criteria

• Experience contributing to publications.
• Experience working within a clinical trial with regards to recruitment, engagement, obtaining data (samples/MRIs) and longitudinal follow up.

The department of Neuroimaging at King's College London (KCL) is an internationally renowned centre focused on advancing our understanding of the human brain and its function using cutting-edge imaging and digital assessment technologies. The department is dedicated to exploring the mechanisms of neurological and psychiatric disorders across the lifespan. It employs a multidisciplinary approach, combining expertise in imaging techniques, computational neuroscience, basic and clinical research., At King's, we believe that the diversity of our community and a culture that is welcoming, open, inclusive and collaborative, are great strengths of the university., Artificial intelligence (AI) is evolving rapidly, and we recognise its growing role in professional work. Applicants may use AI tools to support preparation of their application, for example to research the role or structure written responses. However, applications must reflect the applicant's own work and experience. AI tools should not be used during interviews or assessment activities unless this has been agreed in advance as a reasonable adjustment. Further guidance on the use of AI in recruitment can be found .