Principal Statistical Programmer

JR United Kingdom; Dartford; On-site; GBP 60,000 - 80,000; Full time

Job summary

A leading independent CRO is seeking a Principal Statistical Programmer to lead statistical programming projects remotely from anywhere in the UK. The ideal candidate will have a Bachelor's degree in Statistics, at least 8 years of experience in clinical trial programming, and strong knowledge of SAS. This role offers a healthy work-life balance and flexible working hours.

Benefits

Flexible hours

Work-life balance

Remote work

Qualifications

• 8 years’ experience in clinical trial statistical programming.
• Excellent knowledge of SAS essential, R advantageous.
• Good working knowledge of data structures like CDISC, SDTM, ADaM.

Responsibilities

• Lead statistical programming projects ensuring high-quality deliverables.
• Develop and validate SDTM and ADaM datasets.
• Perform QC reviews and ensure CDISC compliance.

Skills

Statistical programming

SAS

CDISC standards

Biostatistics

R programming

Education

Bachelor’s degree in Statistics, Biostatistics, or Computer Sciences

Masters or Ph.D. in Statistics

Job description

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Principal Statistical Programmer, Dartford

Client: Warman O'Brien

Location: Dartford, United Kingdom

Job Category: Other

EU work permit required: Yes

Job Views:

3

Posted:

26.08.2025

Expiry Date:

10.10.2025

Job Description:

Principal Statistical Programmer | Leading CRO | Home Based | UK |

Join a fast-growing, independent CRO providing a broad range of expertise-based clinical research services to worldwide pharmaceutical, biotechnology, and medical device industries.

Renowned for its high-quality deliverables, exceptional customer service, and flexibility in meeting clients’ needs, this growing organisation offers a flexible, dynamic, and entrepreneurial culture. With ongoing growth and exciting career opportunities, it’s the perfect place to advance your career.

We’re seeking elite Principal Statistical Programmers to join this growing organisation remotely from anywhere in the UK.

What you will be doing:

You’ll lead statistical programming projects, ensuring high-quality, on-time deliverables. This includes developing and validating SDTM and ADaM datasets, performing QC reviews, and ensuring CDISC compliance.

You’ll resolve Pinnacle 21 validation issues, review TLFs for consistency, and contribute to regulatory submissions. You'll also create define.xml files, develop and maintain macros, and perform data integrity checks, while ensuring proper documentation and compliance with SOPs.

What you will need:

• A Bachelor’s degree in Statistics, Biostatistics or Computer Sciences + Masters or PH.D in Statistics.
• 8 years’ experience in clinical trial statistical programming.
• Excellent knowledge of SAS essential with R advantageous.
• Good working knowledge of data structures e.g. CDISC, SDTM, ADaM,
• Understanding of clinical data standards (CDISC), TLFs, and submission guidelines.

What in it for you:

• The opportunity to be involved in a growing organisation.
• Enjoy a healthy work-life balance with flexible hours that fit your lifestyle.
• Fully remote in the UK.

What to do next:

• If this opportunity interests you, please apply now with your CV as the organisation is looking to arrange interviews for Principal Statistical Programmers as soon as possible.

Not what you’re looking for?

• Please contact Jo Fornaciari on [phone] for a confidential discussion about potential opportunities.