Principal Device Development Engineer - Modelling

WISE Campaign; Ware; Hybrid; GBP 40,000 - 60,000; Full time

Job summary

A leading pharmaceutical company is looking for an experienced engineer to support the development of complex combination products. The role involves in silico modelling and collaboration with cross-functional teams to drive product development. Ideal candidates will have a degree in Mechanical or Biomedical Engineering, and experience in medical device development. The position is based in Ware, Hertfordshire, with flexible hybrid working options.

Qualifications

• Proven experience in medical device or combination product development.
• Excellent understanding of mechanical principles and systems.
• Ability to build strong relationships with internal and external stakeholders.

Responsibilities

• Define and implement a strategic approach to in silico modelling.
• Provide technical leadership for in silico modelling within device development.
• Collaborate with cross-functional teams to design test programs.

Skills

In silico modelling

Communication of technical information

Time management

Stakeholder relationship building

Education

Degree in Mechanical Engineering, Biomedical Engineering, or related field

Tools

MATLAB

FEA software (e.g., LS Dyna, Abaqus)

CAD

Job description

We are looking for an experienced and motivated engineer with an expertise in modelling to support the development of complex combination products. This role offers the chance to deliver innovative, patient‑centric devices that improve lives and enable access to life‑changing medicines. You will work in a collaborative environment with multidisciplinary teams, driving technical excellence and ensuring robust product development. We value problem‑solving skills, teamwork, and a passion for delivering high‑quality solutions.

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting‑edge technology to transform people's lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients' needs and have the highest probability of success. We're uniting science, technology, and talent to get ahead of disease together. Our approach to R&D.

In this role you will:

• Define and implement a strategic approach to in silico modelling (FEA and fluids) to support the development and industrialisation of complex combination products, embedding modelling as a vital tool as part of the product development process.
• Provide technical leadership for in silico modelling within device development workstreams.
• Analyse complex multi‑phase technical problems, identifying tailored and cost‑effective in silico modelling approaches appropriate for the scenario.
• Collaborate with a cross functional team to design test programmes to demonstrate device robustness which meet regulatory expectations.
• Collaborate with internal teams and external partners to resolve design, manufacturing, and regulatory challenges.
• Present project updates to senior leaders and supporting design reviews at critical development stages.
• Drive continuous improvement initiatives to enhance modelling approaches, efficiency, and consistency.
• Contribute to the compilation and maintenance of device development documentation, including Design History Files (DHF) and Risk Management Files (RMF).

Basic Qualifications

• Degree (or equivalent) in Mechanical Engineering, Biomedical Engineering, or a related field.
• Deep understanding of in silico modelling tools and approaches (e.g. CAD, FEA, CFD/DEM, MATLAB)
• Proven experience in medical device or combination product development, ideally in injectables and/or respiratory products.
• Excellent understanding of mechanical principles and systems.
• Able to communicate complex technical information to senior stakeholders effectively and concisely.
• Management of suppliers (e.g. external manufacturing suppliers, design consultancies).
• Excellent time management and organizational skills, managing multiple projects of varying complexity simultaneously.
• Ability to build strong relationships with internal and external stakeholders.

Preferred Qualification

• Experience of leading device development matrix teams.
• Experience using explicit dynamic FEA software packages (such as LS Dyna and/or Abaqus).
• Experience solving computational models using cloud‑based and/or HPC platforms.
• Knowledge of design of experiments (DOEs) and design space studies.
• Knowledge of regulatory requirements and industry standards, such as design controls (21 CFR 820.30), EU MDR 2017/745, ISO 14971, ISO 13485, and GMP.
• Authoring of global regulatory submissions and supporting agency interactions (e.g. FDA / EMA / notified bodies).
• Evidence of teamwork, flexibility, and a drive to deliver results.
• Familiarity with plastic injection moulding and device manufacturing processes.

This role is based in the United Kingdom at GSK's R&D site in Ware, Hertfordshire. Flexible hybrid working is available, with occasional travel required.

Join us in delivering innovative solutions that make a difference in patients' lives. Apply today!

Closing Date for Applications: 14th November 2025

Please take a copy of the Job Description, as this will not be available post closure of the advert.

When applying for this role, please use the 'cover letter' of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements. The information that you have provided in your cover letter and CV will be used to assess your application.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.