Principal Computational Scientist: Biology + ML Discovery

Helical; Greater London; On-site; GBP 110,000 - 170,000; Full time

Job summary

Helical is seeking a Principal Computational Scientist/Director to translate foundation models into real-world discovery workflows. You will lead model evaluation and applied use cases, partnering with research, Product and Business Development to turn biology + ML into deliverables that matter for customers.

You will mentor junior colleagues, work with a scaling team, and drive strategy at a time of growth. Strong ML for Genomics, PyTorch proficiency, and excellent communication are essential.

Qualifications

• PhD or MSc with industry ML experience in Genomics.
• Strong understanding of ML/AI methods for biology data.
• Hands-on experience with ML frameworks like PyTorch.
• Leadership experience with small teams and roadmaps.
• Excellent communication to translate science for stakeholders.
• Comfortable in a fast-paced, iterative environment.
• Passion for biology and ML at the intersection.

Responsibilities

• Provide scientific leadership across model evaluation and applied use cases.
• Collaborate with research, Product and Business Development to deliver customer-focused outcomes.
• Mentor and support junior colleagues and scale the team.
• Translate cutting-edge biology + ML into tangible deliverables for customers.

Skills

Genomics ML

Transformers

PyTorch

Leadership

Communication

Education

PhD in Computational Biology/ML/Bioinformatics

MSc with 5+ years in ML for Genomics

Tools

PyTorch

Job description

Helical is seeking a Principal Computational Scientist/Director to translate foundation models into real-world discovery workflows. You will lead model evaluation and applied use cases, partnering with research, Product and Business Development to turn biology + ML into deliverables that matter for customers.

You will mentor junior colleagues, work with a scaling team, and drive strategy at a time of growth. Strong ML for Genomics, PyTorch proficiency, and excellent communication are essential.