Principal Business Analyst SAP Production Planning for Process Industries (PP-PI, EWM, TM)

Lantheus Brand; England; On-site; GBP 82,000 - 139,000; Full time

Job summary

A leading radiopharmaceutical company in the UK is seeking a Principal Business Analyst specializing in SAP Production Planning for Process Industries. This role demands significant expertise in PP-PI, EWM, and TM, alongside proven project delivery in regulated environments. Candidates should have over 8 years of SAP experience, leadership abilities, and excellent communication skills. This position offers a competitive salary range of $111,000 to $185,000 annually and a comprehensive benefits package, making a meaningful impact in healthcare delivery.

Benefits

Comprehensive health benefits

401(k) with company contribution

Generous time off package

Qualifications

• 8+ years SAP experience with 5+ years in S/4HANA/ECC.
• Demonstrated delivery in regulated (GxP) manufacturing environments.
• Deep configuration mastery in PP-PI and EWM.

Responsibilities

• Own the PP-PI design across process instructions.
• Implement capacity planning and coordinate with MES/LIMS.
• Lead integrations across SAP and boundary apps.

Skills

SAP configuration mastery

Stakeholder management

Cross-functional leadership

Documentation skills

Education

8+ years of SAP experience

S/4HANA/ECC experience

Tools

SAP PP-PI

SAP EWM

SAP TM

Job description

Principal Business Analyst, SAP Production Planning for Process Industries (PP-PI, EWM, TM)

Job Category: Information Systems/Reporting

Requisition Number: PRINC003785

• Posted : January 7, 2026
• Full-Time
• On-site

Locations

Showing 1 location

Bedford
Bedford, Town of, MA 01730, USA

Description

Lantheus (NASDAQ: LNTH) is the leading radiopharmaceutical-focused company, delivering life-changing science to enable clinicians to Find, Fight and Follow disease to deliver better patient outcomes. Headquartered in Massachusetts with offices in New Jersey, Canada, Germany, Sweden, Switzerland and United Kingdom, Lantheus has been providing radiopharmaceutical solutions for nearly 70 years.

Today, we’re expanding our portfolio and pipeline across oncology, neurology and cardiology. Through recent acquisitions, along with strategic partnerships across the life sciences ecosystem, we are accelerating our efforts to advance precision medicine and improve patient outcomes around the world.

At Lantheus we are purpose-driven, and every employee plays a vital role in our success. We’re dedicated to cultivating a high-growth, forward-thinking culture where innovation thrives and diverse perspectives drive meaningful progress.

Join us and be part of a company where your contributions make a real impact, because we know someone’s health is in our hands.

Summary of role

We are seeking a Principal Business Analyst, SAP Production Planning for Process Industries (PP-PI, EWM, TM). This position is based in Massachusetts and requires a presence on-site (two/three) days per week, and open to applicants authorized to work for any employer within the United States.

Lantheus operates and maintains a portfolio of manufacturing, supply chain and transportation systems. This role has lead configuration responsibilities for the platform. Detailed configuration scope includes the following:

PP-PI

• Master recipe/phase/operation setup; resource capacities; material quantity calculation; control recipes; PI Sheets/XSteps; process messages; batch classification/derivation; goods movements (GI/GR) and confirmations; variance/settlement.

EWM

• Warehouse structure (storage types/sections/bins), HU types, packaging specs; inbound/outbound processes; staging for process orders; wave/slotting; physical inventory/cycle counts; exception codes; RF framework.

TM

• Dangerous goods master and checks; freight unit building; planning and carrier selection; tendering; event management; charge/settlement; alignment with EWM shipping and external documentation for radioactive shipments.

This Principal Business Analyst is expected to perform high-quality project and support work for his/her stakeholders, continue to build the SAP capability at Lantheus and foster its continued growth within the Lantheus organization.

Key Responsibilities/Essential Functions

Manufacturing – PP‑PI (Process Orders)

• Own the PP‑PI design across process instructions (PI Sheets/XSteps), master recipes, phases, and resources; enable electronic batch records (EBR) with robust batch derivation/determination strategies.
• Build standard work for yield/variance handling, co‑/by‑products, rework, and stability studies; integrate with QM for in‑process controls, sampling, and usage decisions.
• Implement capacity planning/ATP integration and coordinate with MES/LIMS for confirmations and data collection; support serialization/traceability and regulatory reporting.

Warehouse – EWM

• Architect EWM for radio‑pharma operations: storage type/bin strategies, HU management, putaway/picking, staging, wave management, and physical inventory/cycle counting; design packaging specifications for shielded containers and temperature‑controlled handling.
• Enable advanced inbound/outbound (IBD/OBD) flows, dock/yard management as needed, and exception handling; optimise replenishment and production staging (PP‑PI→EWM integration).
• Define RF process flows and user profiles; govern slotting/rearrangement for short‑lived isotopes and controlled materials.

Transportation – TM (Nice to have)

• Configure TM for dangerous goods classification, compliant routing, freight units/orders, carrier selection/tendering, and cost calculation; integrate DG checks for IATA/ADR/DOT‑hazmat rules.
• Align TM with EWM shipping and radioactive generator shipment requirements, including palletization, routing, and weight hand‑offs to external systems.

Quality, Compliance & Validation

• Design solutions aligned to cGMP, 21 CFR Part 11/Annex 11, GDP, and SOX controls; author configuration documentation and support validation (VP, IQ/OQ/PQ), change control, and audit readiness in GxP scope.

Integration & Data

• Lead integrations across SAP (QM, MM, SD, GTS, FSCM), boundary apps (MES/LIMS, PLM, labeling/serial devices), and logistic partners; ensure master data stewardship (materials, batches, resources, recipes, BP, DG data).
• Partner with Finance on cost object flows (orders, cost centers, profit centers) and reporting alignment in S/4; collaborate on inventory/traceability and regulatory exports.

Leadership & Delivery

• Serve as solution owner across PP‑PI/EWM/TM; drive roadmaps, govern design standards, mentor analysts, and guide vendor/partner work.
• Lead workshops, fit‑to‑standard, backlog grooming, and cutover/hypercare; maintain a culture of safety, quality, and continuous improvement.

Requirements

• 8+ years SAP experience with 5+ years in S/4HANA/ECC across PP‑PI, EWM, and knowledge of TM, including at least 2 full‑cycle S/4 implementations.
• Deep configuration mastery (SPRO) in PP‑PI (recipes, phases, PI Sheets/XSteps, batch mgmt), EWM (storage types, HU, waves, slotting, packing specs, RF), and TM (DG settings, freight order management, tendering, charge mgmt).
• Demonstrated delivery in regulated (GxP) manufacturing environments with validated systems and audit trails.
• Hands‑on integration experience with QM, SD, MM, GTS; familiarity with MES/LIMS interfaces and electronic batch records; working knowledge of serialization and cold‑chain processes.
• Strong cross‑functional leadership, stakeholder management, and vendor orchestration; excellent documentation and communication skills.

Preferred Requirements

• Experience in radiopharmaceuticals or life‑sciences manufacturing (isotope generators, sterile compounding, short‑half‑life products) and related dangerous goods compliance (IATA/ADR/DOT).
• Knowledge of PP‑DS for capacity‑constrained scheduling, IBP demand/supply integration, and advanced ATP; exposure to private‑cloud S/4 operations and Fiori role‑based UX.
• Prior work aligning job architecture and posting language with enterprise standards (Principal level).

Core Values

• Let people be their best
• Respect one another and act as one
• Learn, adapt, and win
• Know someone’s health is in our hands
• Own the solution and make it happen

The pay range for this position is between $111,000 and $185,000 annually.

Actual base pay offered may vary depending on a number of factors such as job-related knowledge, skills and experience. Employees in this position are eligible for a discretionary performance-based cash incentive, and depending on the level of the role may be eligible for a discretionary annual equity award. Benefits for this position include a comprehensive health benefits package that includes medical, prescription drug, dental and vision coverage. Other offerings include life and disability benefits, pre‑tax accounts, a 401(k) with company contribution, and a variety of other benefits. In addition, employees are eligible for a generous time off package including paid vacation, holidays, sick days, and paid parental leave. Interested candidates can apply at Lantheus.com. Applications for this position will be accepted until January 22th, 2026.

Lantheus is an equal opportunity employer that provides a workplace free from discrimination. All qualified applicants and employees are considered without regard to race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status or any other characteristic protected by law. Lantheus is an E‑Verify Employer.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the Lantheus Talent Acquisition team at [e-mail].

Equal Opportunity Employer
This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the Know Your Rights notice from the Department of Labor.