Postdoctoral Structural Biologist & Lab Manager

RFCSR; Greater London; On-site; GBP 41,000 - 49,000; Full time

Job summary

University College London (UCL) invites applications for a Postdoctoral Structural Biologist & Lab Manager. The role combines cutting-edge structural biology research with hands-on laboratory leadership in a busy research group.

The successful candidate will apply cryo-EM, X-ray crystallography, and related methods to study macromolecular structures, while overseeing operations, equipment, budgets, and safety. A strong mentoring component supports junior researchers.

Qualifications

• PhD in structural biology, biochemistry, biophysics, molecular biology, or closely related discipline
• Proven research experience in structural biology
• Demonstrated ability to manage laboratory environments and workflows
• Strong publication record in peer-reviewed journals

Responsibilities

• Lead and support structural biology research using techniques such as cryo-EM and X-ray crystallography
• Oversee laboratory operations, maintenance of equipment, and procurement
• Manage budgets and consumables, ensuring cost effectiveness
• Ensure compliance with health and safety regulations
• Mentor/train junior researchers and students to foster a productive research environment

Skills

Lab leadership

Mentoring

Budget management

Safety compliance

Communication

Education

PhD in structural biology or related

Tools

Cryo-EM

X-ray crystallography

Protein expression

Job description

General Description

University College London (UCL) is seeking a highly motivated Postdoctoral Structural Biologist & Lab Manager to join a dynamic research group focused on understanding biological mechanisms at the molecular and structural level. This role combines advanced scientific research with laboratory management responsibilities, offering an opportunity to contribute to cutting-edge structural biology projects while ensuring the efficient operation of a busy research laboratory.

The successful candidate will lead and support structural biology research, applying techniques such as cryo-electron microscopy (cryo-EM), X-ray crystallography, and other biophysical and biochemical approaches to investigate macromolecular structures. The research aims to uncover molecular mechanisms underlying biological processes, contributing to advancements in biomedical science.

In addition to research responsibilities, the role includes overseeing laboratory operations, maintaining equipment, managing budgets and consumables, ensuring compliance with health and safety regulations, and supporting other lab members. The postholder will also contribute to training junior researchers and students, fostering a collaborative and productive research environment.

The position is offered on a full-time, fixed-term basis, providing an excellent opportunity for career development in both academic research and laboratory leadership within a world-leading institution.

Eligibility Criteria

• PhD in structural biology, biochemistry, biophysics, molecular biology, or a closely related discipline
• Proven research experience in structural biology
• Demonstrated ability to manage laboratory environments and workflows
• Strong academic track record, including publications in peer-reviewed journals

Required Expertise/Skills

• Expertise in structural biology techniques such as cryo-EM, X-ray crystallography, or related methods
• Experience with protein expression, purification, and characterization
• Strong analytical and problem-solving skills
• Ability to manage laboratory operations, including equipment maintenance and procurement
• Knowledge of laboratory health and safety standards
• Excellent organisational and time management skills
• Strong communication and mentoring abilities
• Ability to work independently as well as collaboratively within a multidisciplinary team

Salary Details

£41,374 to £49,421 per annum (Grade 7), inclusive of London Allowance