Postdoctoral Research Scientist

EHS; Oxford; Hybrid; GBP 39,000 - 48,000; Full time

Job summary

The CAMS Oxford Institute invites applications for a Postdoctoral Research Scientist to join Tao Dong’s Cancer Immunology and Immunotherapy group. You will design and perform experiments to identify cancer-specific T cells and cross-reactivity with viral antigens, contributing to novel cancer immunotherapy strategies.

Responsibilities include analyzing multiomic data, generating new datasets, and developing T cell lines and TCR-T cells, while supervising students and collaborators.

Qualifications

• PhD/DPhil in T cell immunology or related field.
• Experience with human T cells, cell culture and functional phenotyping.
• Experience with single-cell or bulk RNA sequencing and data analysis.
• High-dimensional flow cytometry experience.
• Strong communication and collaboration skills.
• Experience with multiomics platforms and imaging analysis is advantageous.

Responsibilities

• Design and conduct experiments in T cell immunology.
• Analyse existing multiomic data from patient cohorts and generate new datasets.
• Develop T cell lines, clones and TCR-T cells for further characterisation.
• Supervise students and visiting researchers; contribute to publications.
• Prepare presentations and participate in collaborative research projects.

Skills

T cell immunology

Human T cells

Flow cytometry

RNA sequencing

Data analysis

Scientific communication

Education

PhD in T cell immunology

Tools

Single-cell RNA-seq

Bulk RNA-seq

Multiomics data analysis

Imaging analysis

Job description

Location: CAMS Oxford Institute, Building for Molecular Physiology, Roosevelt Drive, Old Road Campus, Oxford, OX3 7BN Additionally, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Headley Way, Headington, Oxford, OX3 9DS

We are seeking to appoint a Postdoctoral Research Scientist to join Professor Tao Dong’s Cancer Immunology and Immunotherapy group at the CAMS Oxford Institute. The research will focus on identifying and characterising cancer-specific T cells with the potential to cross-react with viral antigens, with the aim of improving understanding of cancer progression and informing new cancer immunotherapy strategies.

You will be responsible for designing and conducting experiments, analysing existing multiomic data from patient cohorts, generating new datasets and developing T cell lines, clones and TCR-T cells for further characterisation. The role also involves analysing scientific data, developing experimental protocols, troubleshooting technical problems, supervising students and visiting researchers, and contributing to publications, presentations and collaborative research projects.

It is essential that you hold, or are close to completing, a PhD/DPhil in T cell immunology (or related discipline), with experience working with human T cells, cell culture and functional phenotyping. Candidates should have experience of single-cell or bulk RNA sequencing and data analysis, high-dimensional flow cytometry, managing independent research and contributing to publications or presentations. Excellent communication, collaboration and research planning skills are also required. Experience working with multiomics platforms and datasets or imaging analysis would be advantageous.

This position is offered full time on a fixed term contract until 31 December 2028 and is funded by the CAMS Core grant.

£39,424 to £47,779 per annum (pro rata) : Research Grade 7. This is inclusive of a pensionable Oxford University Weighting of £1,730 per year (pro rata).