Postdoctoral Research Associate (Fixed Term) (Internal Candidates Only)

University of Cambridge; Cambridge; On-site; GBP 34,000 - 44,000; Full time

Job summary

University of Cambridge, Institute of Metabolic Science (IMS), invites applications for a Postdoctoral Research Associate to map feeding circuitry in human hypothalami from lean and obese donors using single-cell and spatial transcriptomic approaches. The role involves running independent projects and collaborating with a small team of postdocs and PhD students.

The appointment is fixed-term, funded until 31 December 2026, with closing date 30 August 2026 and interview date to be confirmed.

Qualifications

• PhD in neuroscience or related field.
• Experience with single-cell and spatial transcriptomics data generation and analysis.
• Experience in neuroscience of energy balance and metabolism.
• Ability to lead independent research projects and collaborate with others.

Responsibilities

• Generate single-nucleus RNAseq data from human hypothalami of lean and obese donors.
• Generate spatial transcriptomic data from human hypothalami of lean and obese donors.

Skills

Neuroscience

Single-cell transcriptomics

Spatial transcriptomics

Data analysis

Project management

Education

PhD in Neuroscience/Genomics

Tools

R

Python

Seurat/Scanpy

Job description

A Postdoctoral Research Associate position is available within the group of Professor Giles Yeo at the Institute of Metabolic Science (IMS), focused on mapping the feeding circuitry in human hypothalami from under-weight and obese donors, using single cell and spatial transcriptomic approaches. The work is funded by the BBSRC.

Scientists are encouraged to apply if they have substantial practical experience in the neuroscience of energy balance and metabolism. Applicants should have a background in the generation and analysis of single cell and spatial transcriptomics data. The role holder will be responsible for running their own research projects and will work with a small group of post docs and PhD students who have overlapping expertise.

Major Responsibilities Will Be

• Generation of single-nucleus RNAseq and spatial transcriptomic data from human hypothalami of lean and obese donors
• Integrating the single cell and spatial transcriptomic data to form a spatio-cellular map of the human hypothalamus across the weight spectrum

Fixed-term: The funds for this post are available until 31 December 2026 in the first instance.

The closing date for applications is Sunday 30 August 2026

The interview date for the role is to be confirmed

Please quote reference RG50764 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.