Postdoctoral Fellow
The Francis Crick Institute Limited
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Benefits offered by this job
Job summary
The Francis Crick Institute is seeking a highly motivated Postdoctoral Fellow to investigate mechanisms governing eukaryotic cell cycle progression in the Nurse Lab. You will lead an independent project exploring how CDK activity is regulated and coordinates key cell cycle events.
Reporting to senior lab leaders, you will design experiments across cell biology and biochemistry, communicate findings through publications, and mentor PhD researchers in a collaborative environment at Crick.
Qualifications
- PhD in cell biology, molecular genetics, biochemistry, or a related discipline.
- Strong experimental design and data interpretation skills.
- Ability to independently develop and deliver a research project.
- Ability to work effectively within a multidisciplinary and collaborative research environment.
- Strong scientific communication and presentation skills.
- A proactive, creative and curious approach to solving challenging biological questions.
Responsibilities
- Leading an independent research project investigating cell cycle regulation.
- Designing and carrying out experiments using cell biology, molecular genetics and biochemical approaches.
- Analysing CDK regulation and its role in DNA replication, mitosis and cell cycle control.
- Developing and applying new experimental approaches, with training provided where required.
- Collaborating with other lab researchers and contributing to wider lab projects.
- Communicating research findings through publications and scientific presentations.
- Supporting and guiding PhD students where appropriate.
Skills
Education
Job description
Salary for this Role:
From £47,500 with benefits, subject to skills and experience.
Job Title: Postdoctoral Fellow
Reports to: Ryoko Mandeville
Closing Date: 30/Sept/2026 23.59 GMT
Job Description:
Contract term: This is a full-time, fixed term (4 years) position on Crick terms and conditions of employment.
Reporting to: Paul Nurse, Principal Group Leader
The Francis Crick Institute is Europe’s largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on a wide range of biomedical research activities.
The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where researchers can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We’ve removed traditional boundaries of departments, divisions and disciplines. We have the freedom to carry out high-quality, bold research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy.
The Nurse Lab investigates one of the most fundamental questions in biology: how cells control their division.
Using the fission yeast Schizosaccharomyces pombe as a powerful model system for eukaryotic cells, the lab studies how Cyclin Dependent Kinases (CDKs) coordinate DNA replication, mitosis and cell division and control progression through the cell cycle. Our research combines cell biology, molecular genetics, biochemistry and systems biology approaches to uncover the fundamental mechanisms that govern the eukaryotic cell cycle.
We are seeking a creative and highly motivated Postdoctoral Fellow to investigate the mechanisms controlling eukaryotic cell cycle progression.
You will lead an independent research project within the lab exploring how CDK activity is regulated and coordinates key cell cycle events. Depending on your research interests, your work could investigate areas including the G1/S transition, mitotic onset, nuclear transport of cell cycle regulators, CDK substrate phosphorylation or the role of chromatin in CDK regulation.
This is an exciting opportunity to tackle fundamental questions in cell biology within a highly collaborative environment, with scope to develop new approaches, contribute to wider projects and to learn how to support PhD researchers.
- Leading an independent research project investigating cell cycle regulation.
- Designing and carrying out experiments using cell biology, molecular genetics and biochemical approaches.
- Analysing CDK regulation and its role in DNA replication, mitosis and cell cycle control.
- Developing and applying new experimental approaches, with training provided where required.
- Collaborating with other lab researchers and contributing to wider lab projects.
- Communicating research findings through publications and scientific presentations.
- Supporting and guiding PhD students where appropriate.
You will have:
(Minimum criteria*)
- PhD in cell biology, molecular genetics, biochemistry, or a related discipline. *
- Strong experimental design and data interpretation skills.*
- Ability to independently develop and deliver a research project.*
- Ability to work effectively within a multidisciplinary and collaborative research environment.*
- Strong scientific communication and presentation skills.*
- A proactive, creative and curious approach to solving challenging biological questions.*
Everyone who works at the Crick has a valuable role to play in advancing the Crick’s mission and shaping our culture!
- We are bold . We make space for creative, dynamic and imaginative ideas and approaches. We’re not afraid to do things differently.
- We are open . We’re highly collaborative and interactive, and make sure our activities are visible to the outside world.
- We are collegial . We show respect for one another, work cooperatively and support the wider community.
At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences.
Weare a Disability Confident: Committed employer andwant to ensure that everyone can apply and be part of our recruitment processes and sowe'llmake reasonable adjustments if you need them - just let us know when you apply. If you needassistancewith applying (i.e., would like to apply by phone or post)please email: ruby.oluwafemi@crick.ac.uk.
Find out more about life at the Crick.
At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development:
- Visas: Applicants for this role will be eligible for sponsorship to work in the UK
- Generous Leave : 28 days of annual leave, plus three additional days over Christmas and bank holidays.
- Pension Scheme : Defined contribution pension with employer contributions of up to 16%.
- Health & Well-being :
- 24/7 GP consultation services.
- Occupational health services and mental health support programs.
- Eye care vouchers and discounted healthcare plans.
- Work-Life Balance :
- Back-up care for dependents.
- Childcare support allowance.
- Annual leave purchase options.
- Crick Networks offering diverse groups’ support, community and inclusive social events.
- Perks :
- Discounted gym memberships, bike-to-work scheme, and shopping discounts.
- Subsidised on-site restaurant and social spaces for team interaction.
- Career support: A Post-doc to PI programme and other career development activities
Please note you must meet the essential criteria listed within the Role Profile, to have your application reviewed.
We reserve the right to withdraw this advert at any given time due to the number of applications received.
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