PhD Scholarship: Predictive Yeast Genome-Scale Engineering

The University of Manchester; Manchester; On-site; GBP 20,000 - 24,000; Full time

Job summary

The University of Manchester invites applications for a four-year PhD studentship funded in part by UKRI. The successful candidate will receive an annual stipend at the UKRI minimum rate (£21,805) plus £1,000 per year enhancement, and a research training support grant of up to £20,000 for the full four-year programme.

The project will investigate empirical reaction-specific translation efficiency operators within phase-specific GSMMs to predict production efficiency in oleaginous yeasts and

Responsibilities

• Estimate mRNA expression levels required to achieve desired increases in reaction capacity.
• Categorise transcriptionally versus translationally bottlenecked genes under nitrogen limitation.
• Deliver predictive models of PUFA production efficiency across selected oleaginous yeasts.

Job description

The University of Manchester invites applications for a four-year PhD studentship funded in part by UKRI. The successful candidate will receive an annual stipend at the UKRI minimum rate (£21,805) plus £1,000 per year enhancement, and a research training support grant of up to £20,000 for the full four-year programme.

The project will investigate empirical reaction-specific translation efficiency operators within phase-specific GSMMs to predict production efficiency in oleaginous yeasts and