PhD – IL-17 Immune–Cardiac Signalling in Cardiorenal Stress

Laplace Expert Ltd; Birmingham; Hybrid; GBP 20.000 - 23.000; Vollzeit

Zusammenfassung

The University of Birmingham invites applications for a PhD opportunity titled “IL-17 Immune–Cardiac Signalling in Cardiorenal Stress”, exploring how IL-17 inflammatory pathways influence immune–cardiac interactions and arrhythmogenic remodelling in chronic kidney disease. Based in Birmingham, the project combines wet-lab and computational approaches to understand cellular cross-talk in the heart.

Applicants should have strong training in biomedical sciences; the programme emphasises single-cell

Qualifikationen

• Strong biomedical science background required.
• Experience with single-cell datasets preferred.
• Familiarity with cardiac biology and signalling is advantageous.

Aufgaben

• Conduct research on IL-17 signalling and its role in cardiorenal stress.
• Integrate single-cell transcriptomics with functional assays.
• Collaborate with interdisciplinary teams across computational and experimental biology.

Kenntnisse

Single-cell transcriptomics

Cardiac cell biology

Calcium signalling

Ausbildung

PhD level

Jobbeschreibung

PhD – IL-17 Immune–Cardiac Signalling in Cardiorenal Stress

University of Birmingham

United Kingdom

23 November 2026 (no exact cutoff time stated)

About This Opportunity

University of Birmingham advertises PhD – IL-17 Immune–Cardiac Signalling in Cardiorenal Stress, an academic opportunity focusing on IL-17 inflammatory signalling and arrhythmogenic cardiac remodelling in chronic kidney disease in Birmingham.

The project investigates how IL-17 signalling connects immune cells, cardiomyocytes and fibroblasts during chronic kidney disease and whether these interactions promote electrical remodelling and arrhythmias. It combines single-cell and single-nucleus transcriptomic datasets, analyses of atrial versus ventricular cell populations, and mechanistic cardiac-cell studies of calcium handling, contraction and signalling. The work connects computational biology with cellular and whole-organ cardiac physiology.Who This Opportunity Is Best Suited For:Based on the documented subject, this could suit prospective doctoral researchers whose interests specifically align with IL-17 inflammatory signalling and arrhythmogenic cardiac remodelling in chronic kidney disease. The official selection criteria, previous research expectations and preferred preparation should be checked before treating the topic match as evidence of formal eligibility.Potential Challenges / Who May Find It Less Suitable:Material practical considerations include competitive studentship allocation rather than automatically guaranteed funding, the currently unresolved final official application endpoint.Overall Opportunity Assessment:This opportunity is distinguished by its focus on IL-17 inflammatory signalling and arrhythmogenic cardiac remodelling in chronic kidney disease. Its documented methods and collaborations provide a concrete basis for assessing methodological fit; application and financial details should be confirmed against the institution’s vacancy or programme instructions.

IL-17 inflammatory signalling and arrhythmogenic cardiac remodelling in chronic kidney disease Biomedical Sciences

Level PhD

Field IL-17 inflammatory signalling and arrhythmogenic cardiac remodelling in chronic kidney disease

Specialization Biomedical Sciences

Organization Type University

Funding & Compensation

Amount Scholarship

Funding Type Scholarship

Requirements

Education

Experience

Technical Skills Single-cell transcriptomics Cardiac cell biology Calcium signalling