PhD: BRCA2 Loss Sensing with NanoMIPs for Prostate Cancer

The University of Manchester; Manchester; On-site; GBP 20,000 - 24,000; Full time

Job summary

The University of Manchester is inviting applications for a 4-year PhD studentship starting September 2027. The project focuses on developing molecularly imprinted polymer nano particles (nanoMIPs) as stable, synthetic alternatives to antibodies for sensing BRCA2 loss in prostate cancer tissue.

Stipend at the UKRI minimum rate of £21,805 per year plus £1,000 per annum enhancement, plus a research training support grant up to £20,000 for the full four-year programme.

Qualifications

• Research experience in polymer science, cancer biology or biosensing is desirable.

Responsibilities

• Generate high-affinity nanoMIPs against defined BRCA2 regions.
• Develop labelled nanoMIP systems for detecting BRCA2 in protein and cell-based assays.
• Establish and validate a tissue-based assay that distinguishes BRCA2-mutant from wild-type prostate cancers.

Skills

Polymer science

Cancer biology

Biosensing

Education

Bachelor's degree with 2:1

Job description

The University of Manchester is inviting applications for a 4-year PhD studentship starting September 2027. The project focuses on developing molecularly imprinted polymer nano particles (nanoMIPs) as stable, synthetic alternatives to antibodies for sensing BRCA2 loss in prostate cancer tissue.

Stipend at the UKRI minimum rate of £21,805 per year plus £1,000 per annum enhancement, plus a research training support grant up to £20,000 for the full four-year programme.