OSD Formulation & Materials Scientist – Process & Scale-Up

Proclinical Staffing; Stone Cross; On-site; GBP 65,000 - 90,000; Full time

Job summary

Proclinical Staffing, on behalf of a leading global pharmaceutical organisation, is seeking an experienced Materials Characterisation & Formulation Scientist to support drug product development, material changes, and manufacturing process performance prediction.

You will apply expertise in oral solid dosage forms, formulation development, and manufacturing science to understand how material variability affects product quality and process robustness, using laboratory work, data analysis, and

Qualifications

• Degree in Pharmaceutical Sciences, Pharmaceutics, Chemistry, Chemical Engineering, Materials Science, or a related discipline.
• Proven years' experience within pharmaceutical development, pharmaceutical manufacturing, MSAT, process development, or formulation development environments.
• Strong knowledge of oral solid dosage forms (OSD) including tablets and capsules.
• Experience with pharmaceutical manufacturing unit operations including blending, granulation, compression, and film coating.

Responsibilities

• Design and execute formulation and process development studies.
• Evaluate the impact of API and excipient variability on manufacturing performance and product quality.
• Assess supplier changes and material variability through laboratory experimentation and risk assessment activities.
• Develop representative small-scale models of pharmaceutical manufacturing processes.
• Investigate relationships between material attributes, process parameters, and CQAs.
• Conduct studies involving: powder blending; content uniformity; wet granulation; dry granulation; powder flow and feeding behaviour; tablet compression; compaction analysis; tablet sticking investigations; film coating; stability and robustness assessments.
• Support process understanding, scale-up activities, and manufacturability assessments.
• Analyse experimental data and provide scientific recommendations.
• Prepare technical reports, presentations, and project updates.
• Collaborate with multidisciplinary teams including formulation, process, analytical, and manufacturing scientists.

Skills

OSD knowledge

Formulation development

Process development

Manufacturing science

Material characterisation

Pharmaceutical manufacturing

Technical writing

Stakeholder communication

Education

Degree in Pharmaceutical Sciences or related discipline

Job description

Proclinical Staffing, on behalf of a leading global pharmaceutical organisation, is seeking an experienced Materials Characterisation & Formulation Scientist to support drug product development, material changes, and manufacturing process performance prediction.

You will apply expertise in oral solid dosage forms, formulation development, and manufacturing science to understand how material variability affects product quality and process robustness, using laboratory work, data analysis, and