Lead Computational Gene Therapy Design Engineer

GeneEase; Remote; GBP 60,000 - 80,000; Full time

Job summary

A leading gene therapy company in Birmingham is seeking a specialist to lead the development of computational gene therapies. The role involves designing therapeutics that are manufacturable and clinically translatable while ensuring practicality in experimental validation. The ideal candidate will have a PhD in Computational Biology or related fields, alongside hands-on experience in gene therapy. A collaborative mindset and strong technical skills in protein modeling and programming are essential. Flexible work arrangements are available.

Benefits

Flexible work arrangements

Collaboration with a global team

Direct influence on product development

Qualifications

• PhD in a relevant field or MS with 3-5 years experience required.
• 1-3 years hands-on wet lab experience preferred.
• Familiarity with gene therapy techniques and tools.

Responsibilities

• Lead the design of gene therapies focusing on manufacturability and deliverability.
• Validate therapeutic targets in silico and coordinate wet lab experiments.
• Draft manuscripts and patent applications emphasizing clinical applications.

Skills

Protein modeling

Gene therapy experience

Programming in Python

Understanding of manufacturability

Strong communication skills

Education

PhD in Computational Biology or related fields

MS with 3-5 years experience

Tools

AlphaFold

GROMACS

Benchling

SQL

Job description

A leading gene therapy company in Birmingham is seeking a specialist to lead the development of computational gene therapies. The role involves designing therapeutics that are manufacturable and clinically translatable while ensuring practicality in experimental validation. The ideal candidate will have a PhD in Computational Biology or related fields, alongside hands-on experience in gene therapy. A collaborative mindset and strong technical skills in protein modeling and programming are essential. Flexible work arrangements are available.