ICON PLC - Pharmacometrician

Promoting Statistical Insights; Sheffield; On-site; GBP 60,000 - 80,000; Full time

Job summary

A leading healthcare intelligence organization is seeking a Pharmacometrician to contribute to regulatory strategy and pharmacometric analysis. The ideal candidate will possess a Ph.D. and significant experience in model-based methods with tools like NONMEN and Monolix. This role offers a competitive salary and extensive benefits, including health insurance, retirement planning, and flexible benefits for work-life balance. Join a diverse team in Sheffield to shape the future of clinical development.

Benefits

Annual leave entitlements

Health insurance offerings

Retirement planning offerings

Global Employee Assistance Programme

Life assurance

Childcare vouchers

Discounted gym memberships

Qualifications

• 3+ years relevant work experience; 2+ years in applying model-based methods in drug development.
• Expert knowledge in pharmacometrics applications.
• Strong scientific skills in clinical development strategy.

Responsibilities

• Develop and execute pharmacometric analysis plans and reports.
• Drive regulatory/submission strategy and related documents.
• Align with Analytics team on pharmacometric strategy.

Skills

Pharmacometric analysis

Model-based methods

Problem solving

Effective communication

Education

Ph.D. in pharmacology, biology, engineering, mathematics, statistics, or related field

Tools

NONMEN

Monolix

Job description

ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development.

We are currently seeking a Pharmacometrician to join our diverse and dynamic team. As a Pharmacometrician at ICON, you will play a pivotal role in driving the pharmacometric contributions to regulatory/submission strategy and related documents (e.g. briefing books, summaries of clinical pharmacology/efficacy/safety, responses to Health Authority questions) with oversight.

Key Responsibilities:

• Develop, write, and execute pharmacometric analysis plans, and deliver reports on results.
• Drive the pharmacometric contributions to regulatory/submission strategy and related documents (e.g. briefing books, summaries of clinical pharmacology/efficacy/safety, responses to Health Authority questions) with oversight.
• Assess pharmacometric requirements for and ensure integration of pharmacometric information into transition of drug development milestones / decision boards.
• Align with the Analytics team (biometrician, data management, database programming, programming, medical and scientific writing) on the pharmacometric strategy, execution and delivery of assigned projects.

Your Profile

• Ph.D. in pharmacology, biology, engineering, mathematics, statistics, or a field with significant modeling-related content (or equivalent).
• 3+ years relevant work experience; 2+ years in applying model-based methods in preclinical and clinical drug development.
• Expert knowledge and evidence of hands‑on experience in the application of pharmacometrics methods to drug development.
• Scientific skills demonstrated in facilitating the (early/full) clinical development strategy.
• Develop, write, and execute pharmacometric analysis plans, and deliver reports on results.
• Proven work experience with the following tools: NONMEN and Monolix.
• Excellent problem‑solving skills and attention to detail.
• Effective communication skills to collaborate with multidisciplinary teams.

What ICON can offer you

Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent. In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well‑being and work‑life balance opportunities for you and your family.

Our benefits examples include:

• Various annual leave entitlements
• A range of health insurance offerings to suit you and your family’s needs.
• Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
• Global Employee Assistance Programme, LifeWorks, offering 24‑hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family’s well‑being.
• Life assurance
• Flexible country‑specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others.

How to Apply

Please click here to apply!

Statisticians in the Pharmaceutical Industry Executive Office:
St James House | Vicar Lane | Sheffield | S1 2EX | UK