Head of Production

Next Phase Recruitment; Birmingham; Sur place; GBP 70 000 - 90 000; Plein temps

Résumé du poste

A UK pharmaceutical manufacturer is seeking a Head of Manufacturing Operations to ensure compliance and oversee production planning within a GMP-regulated environment. The candidate should have a degree in Pharmacy or a related field, with extensive experience in the industry, especially in operational leadership roles. The role focuses on fostering a high-performing culture, driving process improvements, and ensuring patient safety and regulatory compliance.

Qualifications

• 7+ years in GMP-regulated pharmaceutical manufacturing.
• 3-5 years in operational leadership roles.
• Experience with investigations and CAPA processes.

Responsabilités

• Ensure compliance with SOPs and GMP Standards.
• Oversee production planning and batch execution.
• Lead validation and change initiatives.

Connaissances

GMP compliance

Operational leadership

Lean/Six Sigma methodologies

Analytical problem-solving

Communication skills

Formation

Degree in Pharmacy or related discipline

Description du poste

Head of Manufacturing Operations

Overview

We are seeking an experienced leader to oversee day-to-day operations at a UK-based pharmaceutical manufacturing facility specialising in the production of unlicensed medicines (“specials”). The role requires a balance of strategic leadership and hands-on operational oversight to ensure regulatory compliance, efficiency, and the delivery of high-quality products that put patient safety first.

Key Responsibilities

• Ensure compliance and governance by maintaining SOPs, embedding GMP standards and data integrity practices, and sustaining a trained, competent workforce.
• Oversee production planning by translating forecasts and patient-specific orders into achievable schedules, while managing material flow, segregation, and availability.
• Manage batch execution and documentation to ensure the use of approved records, accurate reconciliation, and timely resolution of queries.
• Maintain facilities and equipment in partnership with Engineering, ensuring calibration, qualification, and effective contamination control measures are in place.
• Lead validation and change initiatives, supporting process validation, technology transfers, and process improvements under change control.
• Drive investigations and improvements by leading root cause analysis, implementing effective CAPAs, and reducing inefficiencies through Lean/Six Sigma methodologies.
• Foster people and culture development by building a high-performing team, setting objectives, coaching staff, and promoting a safety- and quality-first mindset.
• Act as subject matter expert during audits, ensuring the site remains in a constant state of inspection readiness.
• Support GDP and controlled drug management where applicable, ensuring full compliance with licence conditions in collaboration with the Responsible Person.
• Work closely with Quality leadership to jointly oversee compliance, approve controlled documentation, manage supplier performance, review batch records, and maintain readiness for internal and external audits.

Experience and Qualifications

• Degree in Pharmacy, Pharmaceutical Sciences, Chemistry, Microbiology, Engineering, or a related scientific discipline.
• Extensive experience (7+ years) in GMP-regulated pharmaceutical manufacturing, with a strong track record in operational leadership (3-5 years).
• Proven success in achieving production targets while delivering improvements in yield, right-first-time metrics, and deviation rates.
• Demonstrated expertise in investigations, CAPA, change control, and working with cross-functional teams.
• Previous exposure to small-batch or patient-specific manufacturing is highly desirable.

Personal Profile

• Decisive and calm under pressure, with the judgement to prioritise patient safety and compliance above all else.
• Highly detail-oriented, with deep knowledge of GMP and production controls.
• Skilled in planning, resource management, and operational delivery.
• Analytical, data-driven, and confident applying structured problem-solving tools.
• A clear and persuasive communicator, able to connect with both shopfloor teams and senior stakeholders.
• A role model for integrity, GMP behaviours, and a culture of continuous improvement.

Seniority level

• Director

Employment type

• Full-time

Job function

• Production and Management
• Industries: Pharmaceutical Manufacturing and Biotechnology Research

Note: This description focuses on the responsibilities and qualifications for the Head of Manufacturing Operations role at a UK-based pharmaceutical facility.