Genetic Epidemiology Research Fellow — Obesity & Diabetes

Economics Network; Southampton; On-site; GBP 37,000 - 46,000; Full time

Benefits offered by this job

Pension provision

Generous annual leave

Job summary

The University of Southampton invites applications for a full-time, fixed-term Research Fellow to investigate obesity heterogeneity and its impact on type 2 diabetes within a multidisciplinary precision-diabetes programme. You will work at University Hospital Southampton, applying GWAS, Mendelian randomisation and post-GWAS analyses to uncover genetic determinants of metabolic risk.

We seek a PhD in genetic epidemiology or related field with experience in large-scale genetic datasets, R/Python,

Qualifications

• PhD in genetic epidemiology or closely related field.
• Experience analysing large-scale genetic/genomic datasets.
• Strong computational skills in R and/or Python; Linux environment experience.
• Knowledge of GWAS methodology and post-GWAS approaches.
• Knowledge of Mendelian randomisation and causal inference methods.
• Evidence of high-quality research outputs.

Responsibilities

• Investigate genetic and biological heterogeneity of obesity and its relationships with type 2 diabetes and complications.
• Perform GWAS of obesity-related traits and metabolic outcomes using large datasets.
• Apply Mendelian randomisation to explore causal relationships between adiposity, diabetes and complications.
• Conduct post-GWAS analyses (fine-mapping, functional annotation, gene prioritisation).
• Collaborate with multidisciplinary teams to disseminate findings through publications and conferences.
• Contribute to high-quality publications and presentations within an international collaboration.

Skills

GWAS analysis

Mendelian randomisation

R/Python

Genetic epidemiology

Statistical genetics

Education

PhD in genetic epidemiology

Tools

Linux

R

Python

Job description

The University of Southampton invites applications for a full-time, fixed-term Research Fellow to investigate obesity heterogeneity and its impact on type 2 diabetes within a multidisciplinary precision-diabetes programme. You will work at University Hospital Southampton, applying GWAS, Mendelian randomisation and post-GWAS analyses to uncover genetic determinants of metabolic risk.

We seek a PhD in genetic epidemiology or related field with experience in large-scale genetic datasets, R/Python,