Genetic Assays Scientist – PK/PD Bioanalysis

Moderna Therapeutics; Oxford; Hybrid; GBP 90,000 - 120,000; Full time

Job summary

Moderna Therapeutics, based at our Harwell site in Oxfordshire, is seeking a senior scientist to advance pharmacokinetic/pharmacodynamic analyses with a focus on genetic, biochemical and molecular biology assays.

You will work across DNA/RNA isolation, qPCR, ddPCR, RNA sequencing, MSD, ELISA and immunoblotting, establishing internal and partner bioanalytical capabilities while aligning with GLP and GxP expectations.

Qualifications

• Ph.D. required in genetic assays with strong background in bioanalytical science.
• 5+ years of biotech/pharma industry experience (Ph.D. route) or 7+ years with B.S./M.S.
• Expert knowledge of RT-PCR, ddPCR, RNA sequencing and related methodologies.

Responsibilities

• Design and execute phase-appropriate biochemical and molecular assays for PK/PD analyses.
• Qualification/validation of assays per GcLP/GLP for clinical use.
• Collaborate with CROs and internal teams to ensure data quality and regulatory compliance.
• Develop internal mRNA-based bioanalytical capabilities and support portfolio.
• Procure and qualify analytical equipment; maintain SOPs and reagents.
• Stay current with GLP/GCP guidelines and applicable regulations.

Skills

Genetic assays

Molecular biology

qPCR/RTPCR

Data analysis

Regulatory awareness

Education

Ph.D. in genetics/related field

B.S./M.S. with 7+ years experience in bioanalysis

Tools

LIMS

eLNB

Job description

Moderna Therapeutics, based at our Harwell site in Oxfordshire, is seeking a senior scientist to advance pharmacokinetic/pharmacodynamic analyses with a focus on genetic, biochemical and molecular biology assays.

You will work across DNA/RNA isolation, qPCR, ddPCR, RNA sequencing, MSD, ELISA and immunoblotting, establishing internal and partner bioanalytical capabilities while aligning with GLP and GxP expectations.