General Manager

Syneos Health, Inc.; Greater London; Sur place; GBP 180 000 - 240 000; Plein temps

Résumé du poste

Syneos Health in London seeks a General Manager for EU Established Brands to lead cross‑functional teams across Sales, Marketing, Therapeutic Category and Operations. You will own the portfolio P&L, allocate promotional investments and drive revenue and margins in Europe and the UK.

You will partner with senior leadership to deliver program governance, solidify commercial strategy, and ensure high‑quality execution across multiple markets with a strong emphasis on patient and customer outcomes.

Qualifications

• Bachelor’s degree required; Master’s degree preferred with 15+ years of related work experience.
• At least 10 years in senior commercial roles across multiple functional areas in European markets.
• At least 5 years of direct P&L responsibilities for EU/UK assets in a pharmaceutical manufacturer.
• Strong background in marketing, pricing, reimbursement, and building brand value propositions.
• Proven leadership in a complex, matrixed environment and ability to travel as needed.

Responsabilités

• Head the Established Brands team supporting the customer relationship.
• Lead the delivery team to maximize product revenue and margin forecasts.
• Manage program P&L and financial performance for the customer relationship.
• Serve as primary customer and senior Syneos Health leadership contact.
• Ensure compliance with customer policies and procedures with Compliance leadership.
• Lead governance meetings, provide management reporting and strategic recommendations.
• Proactively allocate promotional investments to maximize performance.
• Provide direction for work delegated to vendor partners when needed.
• Develop and deliver senior leadership and ad-hoc presentations and training.

Connaissances

Leadership

Financial acumen

Strategic planning

Communication

Relationship building

Travel availability

Cross-functional collaboration

Formation

Bachelor’s Degree

Master’s Degree preferred

Description du poste

Updated: September 9, 2026
Location: London, England, United Kingdom
Job ID:17907

The GM for EU Established Brands will be responsible for all aspects of the promotion for a portfolio of later stage and potentially earlier stage assets across multiple markets in Europe and the UK on behalf of a customer. The GM will lead a team of Sales, Marketing, Therapeutic Category, and Operations personnel supporting the portfolio and driving sales performance. The person will be responsible for the allocation of promotional investments and resources to maximize the value of the contract relationship.

Job Responsibilities

• Serve at the head of the Established Brands team supporting the contract relationship with the customer
• Manage the broader delivery team to maximize performance against product revenue and margin forecasts
• Manage the P&L associated with the program and be responsible for financial performance of the customer relationship
• Act as the primary point of contact for the customer and senior leadership at Syneos Health
• Liaise with Compliance leadership to maintain compliance with the customer’s policies and procedures
• Participate in the program governance and lead periodic joint steering meetings and provide management reporting, as required
• Anticipate client or program needs and issues before they occur and collaborate to develop effective solutions
• Lead weekly cross-functional meetings to discuss program status, performance, major milestones, and key deliverables to ensure that execution is well planned and met for all open program activities
• Lead the commercial execution and ensure activities and deliverables are consistently completed with the highest quality work, on time, and on budget
• Proactively assess the allocation of promotional investments and resources and propose reallocations to maximize performance
• Apply own knowledge and operational experience to ensure consistent quality and successful execution throughout the lifecycle of the project
• As appropriate, this role provides direction for work delegated to additional vendor partners (outside of Syneos) to ensure quality and timely completion of deliverables or provision of services.
• Develop and deliver Senior Leadership and ad-hoc presentations and training as needed.

Qualifications:

• Bachelor’s Degree required; Master’s Degree preferred with 15+ years of related work experience
• At least 10 years in senior commercial roles that spanned across multiple functional areas (e.g., General Management, Marketing, Access, Sales, Commercial Operations) in European markets
• At least 5 years of direct P&L responsibilities for in-line commercial assets in the EU and UK region for a pharmaceutical manufacturer
• Demonstrated record of success in driving new and established product sales. Strong background in marketing, pricing, reimbursement, creative product/program development, and building optimized brand value propositions
• Financial acumen and the ability to read and understand program financials and manage program P&L is critical
• Proven leadership and influencing within a complex and heavily matrixed environment required
• Deep knowledge of the European pharmaceutical industry and healthcare system trends, financial data, customer insights and needs and be able to translate competitive intelligence data into meaningful short- and long-term actions
• European launch experience across multiple pharmaceutical and therapeutic areas is required – client specific therapeutic area experience strongly preferred, global launch experience is a plus
• Demonstrated commercial ability and business acumen, including strategic and tactical planning and execution
• Ability to build relationships and collaborate with others to achieve mutual objectives both within Syneos, external partners, and the client
• Excellent written and verbal communication skills
• Strong self-awareness and emotional intelligence to effectively lead through change
• Strong leadership attributes to set direction, generate commitment, balance short- and long-term needs, constructively resolve issues
• The ability to work in a comparable time zone to the client and key internal partners is required
• Experience leveraging off-shore and near-shore resources
• Ability to travel as needed

At Syneos Health, we are dedicated to building a diverse, inclusive and authentic workplace.

Syneos Health companies are affirmative action/equal opportunity employers (Minorities/Females/Veterans/Disabled)

Why Syneos Health?

Here, you’re a part of the big picture. You will collaborate with colleagues across clinical and commercial disciplines to guide premarket development through post-market commercial strategy. Every project is a chance to solve a new challenge, learn from your colleagues, and advance your career. The diversification and breadth of our new and existing partnerships create a multitude of career paths and employment opportunities. Join our game-changing, global company dedicated to creating better, smarter, faster ways to get biopharmaceutical therapies to patients. Experience the thrill of knowing that your everyday efforts are contributing to improving patients’ lives around the world.

Discover what our more than 25,000 employees already know: work here matterseverywhere. We work hard,and smart, all in the name of getting much-needed therapies to thosewho need them most. A career with Syneos Health means your everyday workimprovespatients’ lives around the world. Selecting us as an employer secures acareer inwhich you’re guaranteed to:

Syneos Health® is a leading fully integrated biopharmaceutical solutions organization builtto accelerate customer success. We translate unique clinical, medical affairs and commercialinsights into outcomes to address modern market realities. To learn more visit syneoshealth.com .

Syneos Health is an Equal Opportunity Employer. All qualified applicants will receiveconsideration for employment without regard to race, color, age, religion, marital status,ethnicity, national origin, sex, gender, gender identity, sexual orientation, protectedveteran status, disability or any other legally protected status and will not bediscriminated against. If you are an individual with a disability who requires reasonableaccommodation to complete any part of our application process, including the use of thiswebsite, please contact us at: Email: [emailprotected] One of our staff members willwork with you to provide alternate means to submit your application.