Executive Director, Clinical Development Program Lead, Hematology

Jobtailor; Uxbridge; On-site; GBP 120,000 - 180,000; Full time

Job summary

Jobtailor is seeking a senior leader to set and drive the clinical development strategy for multiple assets. You will directly supervise Clinical Development Leads and oversee trial physicians, guiding Phase I–III programs through regulatory submissions.

The role requires an MD with 12+ years in trials, drug development, and regulatory affairs, plus proven matrix leadership and global collaboration experience. Travel may be required as part of a broad lifecycle management agenda.

Qualifications

• MD is required.
• PhD or another high-level degree is optional.
• 12+ years in clinical trial, drug development and regulatory work.
• Management experience is required.
• Global experience is a plus.
• Experience interacting with business development and licensing.
• Proven track record leading complex clinical programs to regulatory submissions.
• Matrix leadership experience across multiple functions.
• Ability to work with cross-functional teams from Research through Regulatory.
• Travel domestically and internationally may be required.

Responsibilities

• Set the clinical development strategy for assets or indications.
• Directly supervise Clinical Development Leads and oversee Clinical Trial Physicians.
• Supervise broad Clinical Development and Disease/Indication Strategy teams.
• Support transitions and benefit-risk assessments with Research, Early Development and Global Drug Development.
• Oversee phase I–III programs and regulatory filings components.
• Lead Clinical Excellence activities, Protocol Review Committee, and governance matters.
• Manage budgets and headcount for the Clinical Development function.
• Mentor talent and foster an ethical, collaborative, accountable culture.
• Collaborate with Commercial, Medical, Regulatory and other functions globally.
• Engage with thought leaders, physicians and patient advocacy groups.

Skills

Clinical leadership

Team mentoring

Cross-functional collaboration

Regulatory submissions

Strategic thinking

Governance & ethics

Education

MD

PhD (Optional)

Job description

• Set the clinical development strategy for assets or indications
• Directly supervise Clinical Development Leads and oversee Clinical Trial Physicians
• Supervise broad Clinical Development and Disease/Indication Strategy teams
• Work with Research and Early Development and Global Drug Development to support transitions and benefit-risk assessments
• Supervise differentiated Clinical Development Programs from Phase I expansion through registrational execution
• Support Clinical Excellence activities, Protocol Review Committee, business development and Quality and Compliance leadership
• Report to the Head of Clinical Development and deputize as required
• Create and communicate innovative clinical development plans
• Supervise development, monitoring, analysis and interpretation of clinical trials
• Oversee clinical components of regulatory filings
• Contribute to disease/indication and franchise portfolio strategy
• Lead business development due diligence search and evaluation activities
• Serve on and chair Therapeutic Area Clinical Development Leadership forums
• Develop programs beyond commercialization and launch into lifecycle management
• Lead, recruit, develop and retain Clinical Development professionals
• Mentor talent and establish an ethical, collaborative and accountable culture
• Oversee team budget and headcount
• Collaborate globally with Research, Development, Regulatory, Medical, Commercial and other functions
• Build relationships with thought leaders, physicians and patient advocacy groups
• Ensure seamless transition from first-in-human and proof-of-concept trials into Phase II–III development
• Participate in governance as designated
• Exercise signature authority for CSRs, Health Authority Briefings, DMC Charters, Unblinding Requests and filing documents

Requirements

• MD required
• PhD or other high level degree optional
• Greater than 12 years of extensive clinical trial, drug development, and regulatory experience
• Management experience required
• Strong scientific background
• Extensive experience designing and conducting Phase I, II and III clinical trials
• Demonstrable success filing regulatory dossiers and prosecuting them through approval
• Global experience is a plus
• Experience interacting with business development and licensing
• Proven track record managing complex clinical programs leading to regulatory submissions
• Deep understanding of biology, targets and translational science
• Extensive experience working with health authorities at all levels
• Ability to support and manage registrational and non-registrational trials
• Ability to execute the BMS R&D People Strategy and lead and develop a matrix team
• Ability to work with Commercial, Medical, and research functions from Research through Regulatory
• Comfortable with cross-functional drug and product development teams and managing in a matrix environment
• Skilled at external interaction and speaking engagements
• Skilled at attracting, developing and retaining skilled professionals
• Domestic and international travel may be required

Core Competencies

Demonstrates extensive expertise in clinical trial design and execution, with a strong focus on regulatory submissions and compliance. Proven ability to lead and develop cross-functional teams while fostering collaboration and ethical practices in clinical development.

Highest-signal resume keywords

• MD
• Clinical Trial Management
• Regulatory Submissions
• Phase I, II, III Clinical Trials
• Leadership and Team Development

Hard Skills

• Clinical Development Strategy
• Clinical Trial Design
• Regulatory Filings
• Data Monitoring and Analysis
• Disease/Indication Strategy
• Business Development Evaluation
• Budget Management
• Translational Science
• Complex Program Management
• Health Authority Interaction

Soft Skills

• Mentoring
• Collaboration
• Communication
• Relationship Building
• Ethical Leadership

Certifications & Qualifications

• MD
• PhD (Optional)

Industry Keywords

• Clinical Development
• Drug Development
• Regulatory Compliance
• Clinical Excellence
• Lifecycle Management
• Global Experience
• Matrix Management
• Thought Leader Engagement
• Patient Advocacy
• Governance Participation