Development Scientist, Nucleic Acid Prep

Oxford Nanopore Technologies; Oxford; On-site; GBP 32,000 - 52,000; Full time

Benefits offered by this job

Attractive bonus

Generous pension contributions

Private healthcare

Excellent starting salary

Job summary

Oxford Nanopore Technologies in Oxford is seeking a Development Scientist to join the Sample Technology team. You will work on the design, development, and performance optimisation of nucleic acid sample preparation workflows, closely aligned with sequencing platforms.

The role involves characterisation, troubleshooting and performance improvements across DNA and RNA workflows, with collaboration across Research and Production. A hands-on lab background is essential.

Qualifications

• Hands-on experience working with nucleic acids, proteins or biomolecular complexes in a laboratory setting.
• Familiarity in executing experiments and troubleshooting with documented results.
• Practical knowledge of chromatographic methods for analysis/purification of biomolecules.
• Expertise with at least one analytical or sequencing-based assay method.
• Ability to maintain accurate experimental records and communicate results clearly.

Responsibilities

• Initial design, iteration and characterisation of biomolecular components within sample prep kits.
• Developing biochemical and sequencing-based assays and method development for chromatography-based assays.
• Protein/DNA complex formation and chromatography-based purification.
• Routine use of nanopore-based single molecule assays.
• Data analysis of experiments and reporting to the team.

Skills

Nucleic acids handling

Troubleshooting experiments

Record keeping

Data analysis

Education

BSc or MSc in Biochemistry, Chemistry or a related field

Tools

HPLC/LC-MS

RT-qPCR

Python/R

NGS platforms

Job description

Oxford Nanopore Technologies in Oxford is seeking a Development Scientist to join the Sample Technology team. You will work on the design, development, and performance optimisation of nucleic acid sample preparation workflows, closely aligned with sequencing platforms.

The role involves characterisation, troubleshooting and performance improvements across DNA and RNA workflows, with collaboration across Research and Production. A hands-on lab background is essential.